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- Table of Contents
Facts about Forkhead box protein E3.
Controls lens vesicle closed and subsequent separation of the lens vesicle from ectoderm (By similarity). Controls the expression of DNAJB1 in a pathway that is a must for the development of the anterior segment of the eye (PubMed:27218149).
Human | |
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Gene Name: | FOXE3 |
Uniprot: | Q13461 |
Entrez: | 2301 |
Belongs to: |
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No superfamily |
Forkhead box protein E3
Mass (kDA):
33.234 kDA
Human | |
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Location: | 1p33 |
Sequence: | 1; NC_000001.11 (47416285..47418052) |
Nucleus.
PMID: 11159941 by Semina E.V., et al. Mutations in the human forkhead transcription factor FOXE3 associated with anterior segment ocular dysgenesis and cataracts.
PMID: 11980846 by Ormestad M., et al. Foxe3 haploinsufficiency in mice: a model for Peters' anomaly.