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- Table of Contents
1 Citations 6 Q&As
Facts about Follistatin-related protein 3.
Involved in bone formation; inhibits osteoclast differentiationc. Involved in hematopoiesis; involved in differentiation of hemopoietic progenitor cells, increases hematopoietic cell adhesion to fibronectin and seems to contribute to the adhesion of hematopoietic precursor cells to the bone marrow stroma.
| Human | |
|---|---|
| Gene Name: | FSTL3 |
| Uniprot: | O95633 |
| Entrez: | 10272 |

| Belongs to: |
|---|
| No superfamily |

FLRG; FLRGFSRP; follistatin-like 3 (secreted glycoprotein); Follistatin-like 3; Follistatin-like protein 3; Follistatin-related gene protein; follistatin-related protein 3; FSTL3
Mass (kDA):
27.663 kDA

| Human | |
|---|---|
| Location: | 19p13.3 |
| Sequence: | 19; NC_000019.10 (676392..683385) |
Expressed in a wide range of tissues.
[Isoform 1]: Secreted.; [Isoform 2]: Nucleus. Although alternative initiation has been demonstrated and resulted in different localization, the major source of nuclear FSTL3 appears not to depend on translation initiation at Met-27 according to.




PMID: 9671416 by Hayette S., et al. FLRG (follistatin-related gene), a new target of chromosomal rearrangement in malignant blood disorders.
PMID: 11459787 by Tortoriello D.V., et al. Human follistatin-related protein: a structural homologue of follistatin with nuclear localization.