GADD45A Antibodies

AND GADD45A ELISA kits, GADD45A Proteins

Many biological assays use antibodies to detect GADD45A, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with GADD45A in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop GADD45A antibodies...

We validate the specificity of these antibodies to GADD45A by testing them on tissues known to express GADD45A positively and negatively. Browse below to find the GADD45A antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing a Western blot for GADD45A? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.

Open the GADD45A Western Blot Guide

GADD45A Infographic by Boster Bio

All GADD45A Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-GADD45A Antibody Picoband®

Western blot analysis of GADD45A using anti-GADD45A antibody (PB9945)

The mechanism behind the LDEVs effect on gastric cancer cells

Human

$370
Cat # PB9945
100 μg/vial

GADD45A (NM_001924) Human Over-expression Lysate

Human

$628
Cat # LS001647
20 µg, 100 µg

Anti-Zebrafish GADD45AA Antibody Picoband®

Western blot analysis of GADD45AA using anti-GADD45AA antibody (AZF1R8Z0)

Zebrafish

$470
Cat # AZF1R8Z0
100 μg/vial

GADD45A (NM_001924) Human Recombinant Protein

Coomassie blue staining of purified GADD45A protein

$1249
Cat # PROTP24522
20 µg

GADD45A Overview

Facts about Growth arrest and DNA damage-inducible protein GADD45 alpha.

GADD45A 3D structure. Source: alphafold

Growth arrest and DNA damage-inducible protein GADD45 alpha (GADD45A)

In T-cells, acts as a regulator of p38 MAPKs by inhibiting p88 phosphorylation and activity (By similarity). Might affect PCNA interaction with some CDK (cell division protein kinase) complexes; stimulates DNA excision repair in vitro and inhibits entry of cells into S phase.

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Gene Information

Human
Gene Name:	GADD45A
Uniprot:	P24522
Entrez:	1647

Family

Belongs to:

GADD45 family

Alternative Names

DDIT-1; DDIT1growth arrest and DNA damage-inducible protein GADD45 alpha; DNA damage-inducible transcript 1 protein; DNA damage-inducible transcript-1; GADD45 alpha; GADD45a; GADD45DNA-damage-inducible transcript 1; growth arrest and DNA-damage-inducible 45 alpha; growth arrest and DNA-damage-inducible, alpha

Molecular Weight

Mass (kDA):
18.336 kDA

Genomic Context


Human

Location:	1p31.3
Sequence:	1; NC_000001.11 (67685201..67688334)

Subcellular Localizations

Nucleus.

Diseases

Malignant Neoplasms
Neoplasms
Growth Arrest
Carcinoma
Cell Transformation, Neoplastic
Leukemia
Genotoxic Stress
Malignant Neoplasm Of Breast
Mammary Neoplasms
Malignant Paraganglionic Neoplasm
Inflammation
Prostatic Neoplasms

Carcinogenesis
Malignant Neoplasm Of Lung
Liver Carcinoma
Malignant Neoplasm Of Prostate
Adenocarcinoma
Malignant Neoplasm Of Pancreas

Interacting Proteins

AICDA
Aicda
DCTN2
ERCC5
GADD45GIP1

MAP2K6
NUCB2
SH3GLB1
TDG

Pathways

Cell Cycle
Dna Repair
Cell Death
Cell Cycle Arrest
Cell Proliferation
Methylation
Cell Growth
Dna Methylation
Demethylation
Induction Of Apoptosis
Dna Demethylation
Localization
Pathogenesis

Senescence
Translation
S Phase
Immune Response
Cell Cycle Checkpoint
Programmed Cell Death
Mitosis

PTMs

Phosphorylation
Methylation
Demethylation
Cleavage
Acetylation
Ubiquitination

Deacetylation
Dephosphorylation
Sumoylation
Hydroxylation
Deamination
Oxidation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GADD45A

References

PMID: 1990262 by Papathanasiou M.A., et al. Induction by ionizing radiation of the gadd45 gene in cultured human cells: lack of mediation by protein kinase C.

PMID: 8226988 by Hollander M.C., et al. Analysis of the mammalian gadd45 gene and its response to DNA damage.