GBP5 Antibodies

AND GBP5 ELISA kits, GBP5 Proteins

Many biological assays use antibodies to detect GBP5, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with GBP5 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop GBP5 antibodies...

We validate the specificity of these antibodies to GBP5 by testing them on tissues known to express GBP5 positively and negatively. Browse below to find the GBP5 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing a Western blot for GBP5? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.

Open the GBP5 Western Blot Guide

Designing an IHC experiment for GBP5? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the GBP5 IHC Guide

GBP5 Infographic by Boster Bio

All GBP5 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-Guanylate-binding protein 5 GBP5 Antibody

Western blot analysis of GBP5 in rat liver tissue lysate with GBP5 antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide

Immunohistochemistry of GBP5 in human liver tissue with GBP5 antibody at 2

Immunofluorescence of GBP5 in human liver tissue with GBP5 antibody at 20 μg/ml

Human, Mouse, Rat

ELISA, IF, IHC-P, WB

$481
Cat # A07110
0.1 mg

GBP5 (NM_052942) Human Over-expression Lysate

GBP5 Human Over-expression Lysates NM_001134486

Human

$628
Cat # LS115362
20 µg, 100 µg

Anti-GBP5 Antibody

Human, Mouse

ELISA, Flow Cytometry, IP, IF, IHC, ICC, WB

$370
Cat # A07110-1
100 μl/vial

GBP5 (NM_052942) Human Recombinant Protein

Coomassie blue staining of purified GBP5 protein

$1249
Cat # PROTQ96PP8
20 µg

GBP5 Overview

Facts about Guanylate-binding protein 5.

GBP5 3D structure. Source: alphafold

Guanylate-binding protein 5 (GBP5)

As an activator of NLRP3 inflammasome meeting, plays a role in innate immunity and inflammation. Promotes selective NLRP3 inflammasome meeting in response to microbial and soluble, but not crystalline, agents (PubMed:22461501).

Hydrolyzes GTP, but in contrast to other family members, doesn't create GMP (PubMed:20180847). .

Gene Information

Human
Gene Name:	GBP5
Uniprot:	Q96PP8
Entrez:	115362

Family

Belongs to:

TRAFAC class dynamin-like GTPase superfamily

Alternative Names

GBP-5; GBP-TA antigen; GTP-binding protein 5; Guanine nucleotide-binding protein 5; guanylate binding protein 5; guanylate-binding protein 5

Molecular Weight

Mass (kDA):
66.617 kDA

Genomic Context


Human

Location:	1p22.2
Sequence:	1; NC_000001.11 (89258950..89272860, complement)

Tissue Specificity

Expressed in peripheral blood monocytes (at protein level).

Subcellular Localizations

Cytoplasm. Golgi apparatus membrane; Lipid-anchor.

Diseases

Melanoma
Lymphoma
Inflammation
Infectious Mononucleosis
Lymphoma, T-cell, Cutaneous
Endometrial Polyp
Malignant Neoplasm Of Urinary Bladder
Carcinoma
Superficial Bladder Cancer
Tumor Angiogenesis
Neoplasms
Refractory Angina

Tissue Damage
T-cell Lymphoma
Cell Invasion
Skin Neoplasms
Epstein-barr Virus Infections
Angina Pectoris
Virus Diseases

Pathways

Immune Response
Secretion
Transport
Cell Proliferation
Muscle Contraction
Pyroptosis
Virulence
Macrophage Activation
Decidualization
Tissue Development

Translation
Cell Death
Skeletal Muscle Contraction
Angiogenesis

PTMs

Prenylation

Cleavage

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GBP5

References

PMID: 15175044 by Fellenberg F., et al. GBP-5 splicing variants: New guanylate-binding proteins with tumor- associated expression and antigenicity.

PMID: 17266443 by Tripal P., et al. Unique features of different members of the human guanylate-binding protein family.