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- Table of Contents
GAS6 Antibodies
AND GAS6 ELISA kits, GAS6 Proteins
Many biological assays use antibodies to detect GAS6, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with GAS6 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop GAS6 antibodies...
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GAS6 Infographic by Boster Bio
All GAS6 Products
Product
Figures
Specificity
Applications
Price
Mouse GAS6 ELISA Kit PicoKine®
2 Citations 7 Q&As
Mouse
ELISA
$499
Cat # EK1196
96 wells/kit, with removable strips.
Cat # EK1196
96 wells/kit, with removable strips.
Anti-GAS 6/GAS6 Antibody Picoband®
1 Citations 17 Q&As
Human, Mouse, Rat
Flow Cytometry, IHC, WB
$370
Cat # A00608-1
100 μg/vial
Cat # A00608-1
100 μg/vial
Human GAS6 ELISA Kit PicoKine®
1 Citations 5 Q&As
Human
ELISA
$499
Cat # EK1992
96 wells/kit, with removable strips.
Cat # EK1992
96 wells/kit, with removable strips.
GAS6 Overview
Facts about Growth arrest-specific protein 6.
Growth arrest-specific protein 6 (GAS6)
Ligand for tyrosine-protein kinase receptors AXL, TYRO3 and MER whose signaling is implicated in cell growth and survival, cell adhesion and cell migration. GAS6/AXL signaling plays a role in various processes such as endothelial cell survival through acidification by preventing apoptosis, optimal cytokine signaling through human natural killer cell growth, hepatic regeneration, gonadotropin-releasing hormone neuron survival and migration, platelet activation, or regulation of thrombotic responses.
.
Gene Information
| Human | |
|---|---|
| Gene Name: | GAS6 |
| Uniprot: | Q14393 |
| Entrez: | 2621 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
AXLLG; AXLLGAXL stimulatory factor; AXSFAXL receptor tyrosine kinase ligand; DKFZp666G247; FLJ34709; Gas6; GAS-6; growth arrest-specific 6; growth arrest-specific protein 6
Molecular Weight
Mass (kDA):
74.925 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 13q34 |
| Sequence: | 13; NC_000013.11 (113820549..113864076, complement) |
Tissue Specificity
Plasma. Isoform 1 and isoform 2 are widely expressed, isoform 1 being expressed at higher levels than isoform 2 in most tissues. Isoform 2 is the predominant form in spleen.
Subcellular Localizations
Secreted.
Diseases
- Malignant Neoplasms
- Neoplasms
- Growth Arrest
- Inflammation
- Myeloproliferative Syndrome, Transient
- Tissue Adhesions
- Thrombosis
- Nervousness
- Kidney Diseases
- Carcinoma
- Neoplasm Metastasis
- Atherosclerosis
- Autoimmune Reaction
Interacting Proteins
- AXL
Pathways
- Phagocytosis
- Cell Proliferation
- Coagulation
- Cell Growth
- Secretion
- Pathogenesis
- Cell Adhesion
- Cell Death
- Blood Coagulation
- Platelet Aggregation
- Cell Cycle
- Hemostasis
- Cell Migration
PTMs
- Phosphorylation
- Gamma-carboxylation
- Cleavage
- Carboxylation
- Glycosylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GAS6
bosterbio.com/bosterbio-gene-info-cards/GAS6
References
PMID: 8336730 by Manfioletti G., et al. The protein encoded by a growth arrest-specific gene (gas6) is a new member of the vitamin K-dependent proteins related to protein S, a negative coregulator in the blood coagulation cascade.
PMID: 15108283 by Munoz X., et al. Human vitamin K-dependent GAS6: gene structure, allelic variation, and association with stroke.
1 Publications of Boster GAS6 Antibodies & ELISA Kits
- PubMed ID: -, Chun Wang,Bin Wang,Maimaiti Aili,Shixia Huo,Meng-ting Han,Silafu Aibai,Zhi-Jian ...
*More publications can be found for each product on its corresponding product page