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- Table of Contents
GOT2 Antibodies
AND GOT2 ELISA kits, GOT2 Proteins
Many biological assays use antibodies to detect GOT2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with GOT2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop GOT2 antibodies...
Designing a Western blot for GOT2? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the GOT2 Western Blot GuideDesigning an IHC experiment for GOT2? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the GOT2 IHC GuideGOT2 Infographic by Boster Bio
All GOT2 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A05998-1
100 μg/vial
Cat # A05998-1
100 μg/vial
GOT2 Overview
Facts about Aspartate aminotransferase, mitochondrial.
Aspartate aminotransferase, mitochondrial (GOT2)
Catalyzes the irreversible transamination of the L- tryptophan metabolite L-kynurenine to form kynurenic acid (KA). Plays a crucial role in amino acid metabolism.
Significant for metabolite exchange between mitochondria and cytosol. Facilitates cellular uptake of long-chain free fatty acids.
Gene Information
| Human | |
|---|---|
| Gene Name: | GOT2 |
| Uniprot: | P00505 |
| Entrez: | 2806 |
Family
| Belongs to: |
|---|
| class-I pyridoxal-phosphate-dependent aminotransferase family |
Alternative Names
aspartate aminotransferase, mitochondrial; EC 2.6.1; EC 2.6.1.1; FABP-1; FABPpm; Fatty acid-binding protein; FLJ40994; Glutamate oxaloacetate transaminase 2; glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate aminotransferase2); KAT4; KATIV; kynurenine aminotransferase IV; mAspAT; mitAAT; Plasma membrane-associated fatty acid-binding protein; Transaminase A
Molecular Weight
Mass (kDA):
47.518 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 16q21 |
| Sequence: | 16; NC_000016.10 (58707131..58734316, complement) |
Subcellular Localizations
Mitochondrion matrix. Cell membrane. Exposure to alcohol promotes translocation to the cell membrane.
Diseases
- Carcinoma
- Neoplasms
- Medullary Carcinoma Of Thyroid
- Malignant Neoplasm Of Thyroid
- Hyperplastic Polyp
- Thyroid Neoplasm
- Kidney Neoplasm
- Sarcoma
- Carcinoid Tumor
- Osteoporosis
- Fatty Liver
- Bladder Neoplasm
Pathways
- Localization
- Chromosome Localization
- Cell Adhesion
- Pathogenesis
PTMs
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GOT2
bosterbio.com/bosterbio-gene-info-cards/GOT2
References
PMID: 3207426 by Pol S., et al. Nucleotide sequence and tissue distribution of the human mitochondrial aspartate aminotransferase mRNA.
PMID: 4052435 by Martini F., et al. The primary structure of mitochondrial aspartate aminotransferase from human heart.
1 Publications of Boster GOT2 Antibodies & ELISA Kits
- PubMed ID: 10.3892/mmr.2014.3019, Protein extracts of Crassostrea gigas alleviate CCl4-induced hepatic fibrosis in...
*More publications can be found for each product on its corresponding product page