GSTA4 Antibodies

AND GSTA4 ELISA kits, GSTA4 Proteins

Many biological assays use antibodies to detect GSTA4, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with GSTA4 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop GSTA4 antibodies...

We validate the specificity of these antibodies to GSTA4 by testing them on tissues known to express GSTA4 positively and negatively. Browse below to find the GSTA4 antibody that suites your experiment. We have 6 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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GSTA4 Infographic by Boster Bio

All GSTA4 Products

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Specificity

Applications

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Anti-GSTA4 Antibody Picoband®

Western blot analysis of GSTA4 using anti-GSTA4 antibody (A03699-1)

IHC analysis of GSTA4 using anti-GSTA4 antibody (A03699-1)

Flow Cytometry analysis of U20S cells using anti-GSTA4 antibody (A03699-1)

Human, Monkey

ELISA, Flow Cytometry, IHC, WB

$370
Cat # A03699-1
100 μg/vial

Anti-GSTA4 Antibody Picoband®

Western blot analysis of GSTA4 using anti-GSTA4 antibody (A03699-2)

Mouse, Rat

ELISA, WB

$370
Cat # A03699-2
100 μg/vial

GSTA4 (NM_001512) Human Recombinant Protein

Coomassie blue staining of purified GSTA4 protein

$1249
Cat # PROTO15217
20 µg

Anti-GSTA4 Mouse Monoclonal Antibody [Clone ID: OTI3F5]

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY GSTA4 (Right lane) cDNA for 48 hrs and lysed

Human

Flow Cytometry, IHC, WB

$523
Cat # M03699
100 µl

GSTA4 (NM_001512) Human Over-expression Lysate

Human

$628
Cat # LS002941
20 µg, 100 µg

Anti-GSTA4 Rabbit Monoclonal Antibody

Western blot analysis of GSTA4 expression in 293T cell lysate

All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature

Human, Rat

$370
Cat # M03699-1
100 µl/vial

GSTA4 Overview

Facts about Glutathione S-transferase A4.

GSTA4 3D structure. Source: alphafold

Glutathione S-transferase A4 (GSTA4)

Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. This isozyme has a high catalytic efficiency with 4-hydroxyalkenals such as 4- hydroxynonenal (4-HNE).

Gene Information

Human
Gene Name:	GSTA4
Uniprot:	O15217
Entrez:	2941

Family

Belongs to:

GST superfamily

Alternative Names

DKFZp686D21185; EC 2.5.1.18; glutathione S-alkyltransferase A4; glutathione S-aralkyltransferase A4; glutathione S-aryltransferase A4; glutathione S-transferase A4; Glutathione S-transferase A4-4; glutathione S-transferase alpha 4; glutathione transferase A4-4; GST class-alpha member 4; GSTA4-4; GTA4; S-(hydroxyalkyl)glutathione lyase A4

Molecular Weight

Mass (kDA):
25.704 kDA

Genomic Context


Human

Location:	6p12.2
Sequence:	6; NC_000006.12 (52977952..52995332, complement)

Tissue Specificity

Expressed at a high level in brain, placenta, and skeletal muscle and much lower in lung and liver.

Subcellular Localizations

Cytoplasm.

Diseases

Malignant Neoplasms
Carcinogenesis
Carcinoma
Neoplasms
Liver Carcinoma
Adenoma
Adenocarcinoma
Insulin Resistance
Obesity
Malignant Tumor Of Colon
Malignant Paraganglionic Neoplasm
Infarction

Diabetes Mellitus
Inflammation
Colonic Neoplasms
Dysplasia
Hepatocarcinogenesis
Liver Cirrhosis
Dna Adduction

Interacting Proteins

C2orf50
GSTA2

Pathways

Fermentation
Transport
Cell Cycle
Conjugation
Methylation
Regeneration
Pathogenesis
Dna Hypermethylation
Aging
Glucose Transport
Cell Proliferation
Dna Methylation
Localization

Tissue Regeneration
Cell Growth
Cell Adhesion
Response To Paraquat
Inflammatory Response
Embryo Development
Response To Oxidative Stress

PTMs

Phosphorylation
Methylation
Glutathionylation

Cleavage
Reduction
Acetylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GSTA4

References

PMID: 9461507 by Hubatsch I., et al. Human glutathione transferase A4-4: an alpha class enzyme with high catalytic efficiency in the conjugation of 4-hydroxynonenal and other genotoxic products of lipid peroxidation.

PMID: 9480897 by Board P.G.; Identification of cDNAs encoding two human alpha class glutathione transferases (GSTA3 and GSTA4) and the heterologous expression of GSTA4-4.