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- Table of Contents
HDGF Antibodies
AND HDGF ELISA kits, HDGF Proteins
Many biological assays use antibodies to detect HDGF, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with HDGF in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop HDGF antibodies...
Designing a Western blot for HDGF? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the HDGF Western Blot GuideHDGF Infographic by Boster Bio
All HDGF Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A01057
100 μg/vial
Cat # A01057
100 μg/vial
Human
ELISA, Flow Cytometry, IF, ICC, WB
$370
Cat # A32401-2
100 µg/vial
Cat # A32401-2
100 µg/vial
Human, Mouse
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M01057-1
100 μl/vial
Cat # M01057-1
100 μl/vial
Mouse
Cell Culture
$77
Cat # PROTP51859
5ug,20ug,100ug
Cat # PROTP51859
5ug,20ug,100ug
Human
Cell Culture
$77
Cat # PROTP51858-2
5ug,20ug,100ug
Cat # PROTP51858-2
5ug,20ug,100ug
HDGF Overview
Facts about Hepatoma-derived growth factor.
Hepatoma-derived growth factor (HDGF)
Heparin-binding protein, with mitogenic activity for fibroblasts. Acts as a transcriptional repressor.
.
Gene Information
| Human | |
|---|---|
| Gene Name: | HDGF |
| Uniprot: | P51858 |
| Entrez: | 3068 |
Family
| Belongs to: |
|---|
| HDGF family |
Alternative Names
FLJ96580; HDGF; hepatoma-derived growth factor (high-mobility group protein 1-like); hepatoma-derived growth factor; High mobility group protein 1-like 2; HMG-1L2; HMG1L2DKFZp686J1764; HuHGF
Molecular Weight
Mass (kDA):
26.788 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 1q23.1 |
| Sequence: | 1; NC_000001.11 (156742107..156752448, complement) |
Tissue Specificity
Ubiquitous.
Subcellular Localizations
[Isoform 1]: Nucleus. Cytoplasm. Secreted, extracellular exosome. Secreted by exosomes and is located inside the exosome (PubMed:27926477). May also be secreted as free protein via an as yet unknown pathway (PubMed:27926477).; [Isoform 2]: Nucleus. Cytoplasm. Secreted, extracellular exosome. Secreted by exosomes and is located on the outer exosome surface.; [Isoform 3]: Nucleus. Cytoplasm. Secreted, extracellular exosome. Secreted by exosomes and is located on the outer exosome surface.
Diseases
- Malignant Neoplasms
- Neoplasms
- Liver Carcinoma
- Carcinoma
- Cell Invasion
- Cell Transformation, Neoplastic
- Malignant Neoplasm Of Lung
- Liver Neoplasms
- Non-small Cell Lung Carcinoma
- Tumor Angiogenesis
- Malignant Paraganglionic Neoplasm
- Lung Neoplasms
Pathways
- Cell Proliferation
- Cell Growth
- Localization
- Angiogenesis
- Secretion
- Cell Migration
- Pathogenesis
- Liver Development
- Hepatocyte Proliferation
- Cell Cycle
- Cell Differentiation
- Regeneration
- Chromatin Remodeling
PTMs
- Phosphorylation
- Dephosphorylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/HDGF
bosterbio.com/bosterbio-gene-info-cards/HDGF
References
PMID: 7929202 by Nakamura H., et al. Molecular cloning of complementary DNA for a novel human hepatoma- derived growth factor. Its homology with high mobility group-1 protein.
PMID: 11751870 by Kishima Y., et al. Hepatoma-derived growth factor stimulates cell growth after translocation to the nucleus by nuclear localization signals.