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- Table of Contents
Protein Hook homolog 3 Antibodies
AND HOOK3 ELISA kits, Protein Hook homolog 3 Proteins
Many biological assays use antibodies to detect Protein Hook homolog 3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Protein Hook homolog 3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Protein Hook homolog 3 antibodies...
Designing a Western blot for Protein Hook homolog 3? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the HOOK3 Western Blot GuideHOOK3 Infographic by Boster Bio
All HOOK3 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A07701-1
100 μg/vial
Cat # A07701-1
100 μg/vial
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A07714-1
100 μg/vial
Cat # A07714-1
100 μg/vial
Human, Monkey, Mouse, Rat
ELISA, Flow Cytometry, WB
$370
Cat # A07705-1
100 μg/vial
Cat # A07705-1
100 μg/vial
Human, Mouse, Rat
ELISA, IF, IHC-P, WB
$481
Cat # A07701
0.1 mg
Cat # A07701
0.1 mg
HOOK3 Overview
Facts about Protein Hook homolog 3.
Protein Hook homolog 3 (HOOK3)
Probably serves as a target for the spiC protein from Salmonella typhimurium, which inactivates it, leading to a strong alteration in cellular trafficking (By similarity). Part of the FTS/Hook/FHIP complex (FHF complex).
The FHF complex may function to promote vesicle trafficking and/or mix through the homotypic vesicular protein sorting complex (the HOPS complex). May regulate clearance of endocytosed receptors like MSR1.
Gene Information
| Human | |
|---|---|
| Gene Name: | HOOK3 |
| Uniprot: | Q86VS8 |
| Entrez: | 84376 |
Family
| Belongs to: |
|---|
| hook family |
Alternative Names
FLJ31058; hHK3; HK3h-hook3; hook homolog 3 (Drosophila); protein Hook homolog 3
Molecular Weight
Mass (kDA):
83.126 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 8p11.21 |
| Sequence: | 8; NC_000008.11 (42896978..43030535) |
Subcellular Localizations
Cytoplasm, cytoskeleton. Golgi apparatus. Enriched at the cis-face of the Golgi complex. Localizes to microtubule asters in prophase (PubMed:11238449). Localizes to the manchette in elongating spermatids (By similarity).
Diseases
- Neoplasms
- Malignant Neoplasm Of Prostate
- Syndactyly Of Toes With Fusion Of Bones
- Nerve Degeneration
- Neurodegenerative Disorders
- Schizophrenia
- Ret/ptc Rearrangement
- Neurotoxicity Syndromes
- Tissue Adhesions
- Carcinoma, Papillary
- Oncogene Fusion
- Malignant Neoplasm Of Lung
Interacting Proteins
- HOOK1
- MSR1
Pathways
- Localization
- Cell Adhesion
- Secretory Pathway
- Phagosome-lysosome Fusion
- Golgi Localization
- Nuclear Migration
- Neurogenesis
- Interkinetic Nuclear Migration
- Endocytosis
PTMs
- Acetylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/HOOK3
bosterbio.com/bosterbio-gene-info-cards/HOOK3
References
PMID: 11238449 by Walenta J.H., et al. The Golgi-associated hook3 protein is a member of a novel family of microtubule-binding proteins.
PMID: 17237231 by Sano H., et al. The microtubule-binding protein Hook3 interacts with a cytoplasmic domain of scavenger receptor A.