This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
HPGD Antibodies
AND HPGD ELISA kits, HPGD Proteins
Many biological assays use antibodies to detect HPGD, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with HPGD in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop HPGD antibodies...
Designing a Western blot for HPGD? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the HPGD Western Blot GuideDesigning an IHC experiment for HPGD? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the HPGD IHC GuideHPGD Infographic by Boster Bio
All HPGD Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A02686-3
100 μg/vial
Cat # A02686-3
100 μg/vial
Human
$628
Cat # LS003248
20 µg, 100 µg
Cat # LS003248
20 µg, 100 µg
SDS-PAGE
$250
Cat # PROTO60760
Starting from 20ug
Cat # PROTO60760
Starting from 20ug
HPGD Overview
Facts about 15-hydroxyprostaglandin dehydrogenase [NAD(+)].
15-hydroxyprostaglandin dehydrogenase [NAD(+)] (HPGD)
Prostaglandin inactivation. Contributes to the regulation of events which are under the control of prostaglandin levels.
Catalyzes the NAD-dependent dehydrogenation of lipoxin A4 to form 15-oxo-lipoxin A4. Inhibits in vivo proliferation of colon cancer cells.
Gene Information
| Human | |
|---|---|
| Gene Name: | HPGD |
| Uniprot: | P15428 |
| Entrez: | 3248 |
Family
| Belongs to: |
|---|
| short-chain dehydrogenases/reductases (SDR) family |
Alternative Names
15-hydroxyprostaglandin dehydrogenase [NAD+]; 15PGDH; 15-PGDH; EC 1.1.1; EC 1.1.1.141; HPGD; hydroxyprostaglandin dehydrogenase 15-(NAD); NAD+-dependent 15-hydroxyprostaglandin dehydrogenase; PGDH1; PGDH1PGDH; Prostaglandin dehydrogenase 1; SDR36C1; short chain dehydrogenase/reductase family 36C, member 1
Molecular Weight
Mass (kDA):
28.977 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 4q34.1 |
| Sequence: | 4; NC_000004.12 (174490175..174522898, complement) |
Tissue Specificity
Detected in colon epithelium (at protein level).
Subcellular Localizations
Cytoplasm.
Diseases
- Malignant Neoplasms
- Neoplasms
- Osteoarthropathy, Primary Hypertrophic
- Hypertrophy
- Clubbing
- Osteoarthropathy
- Clubbed Fingers
- Colorectal Cancer
- Colorectal Neoplasms
- Carcinoma
- Cell Transformation, Neoplastic
- Pachyderma
Pathways
- Transport
- Pathogenesis
- Ovulation
- Reverse Transcription
- Cell Cycle
- Cell Growth
- Luteinization
- Rna Interference
- Keratinization
- Cell Migration
- Keratinocyte Differentiation
- Vasculogenesis
- Chemotaxis
PTMs
Research Areas
- Cancer
- Immunology
- Innate Immunity
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/HPGD
bosterbio.com/bosterbio-gene-info-cards/HPGD
References
PMID: 2337593 by Krook M., et al. Purification and structural characterization of placental NAD(+)- linked 15-hydroxyprostaglandin dehydrogenase. The primary structure reveals the enzyme to belong to the short-chain alcohol dehydrogenase family.
PMID: 1697582 by Ensor C.M., et al. Cloning and sequence analysis of the cDNA for human placental NAD(+)- dependent 15-hydroxyprostaglandin dehydrogenase.