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- Table of Contents
HSD17B2 Antibodies
AND HSD17B2 ELISA kits, HSD17B2 Proteins
Many biological assays use antibodies to detect HSD17B2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with HSD17B2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop HSD17B2 antibodies...
Designing a Western blot for HSD17B2? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the HSD17B2 Western Blot GuideHSD17B2 Infographic by Boster Bio
All HSD17B2 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse
ELISA, Flow Cytometry, IF, ICC, WB
$370
Cat # A02506-1
100 µg/vial
Cat # A02506-1
100 µg/vial
Human
Flow Cytometry, WB
$523
Cat # M02506
100 µl
Cat # M02506
100 µl
HSD17B2 Overview
Facts about Estradiol 17-beta-dehydrogenase 2.
Estradiol 17-beta-dehydrogenase 2 (HSD17B2)
Capable of catalyzing the interconversion of testosterone and androstenedione, as well as estradiol and estrone. Also has 20-alpha-HSD activity.
Uses NADH while EDH17B3 utilizes NADPH. .
Gene Information
| Human | |
|---|---|
| Gene Name: | HSD17B2 |
| Uniprot: | P37059 |
| Entrez: | 3294 |
Family
| Belongs to: |
|---|
| short-chain dehydrogenases/reductases (SDR) family |
Alternative Names
17-beta-hydroxysteroid dehydrogenase type 2; 20 alpha-hydroxysteroid dehydrogenase; E2DH; EC 1.1.1.62,17-beta-HSD 2; EC 1.1.1.63; EDH17B220-alpha-HSD; estradiol 17-beta-dehydrogenase 2; HSD17; hydroxysteroid (17-beta) dehydrogenase 2; Microsomal 17-beta-hydroxysteroid dehydrogenase; SDR9C2; short chain dehydrogenase/reductase family 9C, member 2; Testosterone 17-beta-dehydrogenase
Molecular Weight
Mass (kDA):
42.785 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 16q23.3 |
| Sequence: | 16; NC_000016.10 (82035253..82098534) |
Subcellular Localizations
Membrane; Single-pass type II membrane protein.
Diseases
- Malignant Neoplasms
- Neoplasms
- Malignant Neoplasm Of Breast
- Endometrial Polyp
- Mammary Neoplasms
- Endometriosis, Site Unspecified
- Malignant Neoplasm Of Prostate
- Prostatic Neoplasms
- Endometrial Neoplasms
- Endometrial Carcinoma
- Steroid Sulfatase Deficiency Disease
- Carcinoma
Pathways
- Pathogenesis
- Secretion
- Localization
- Methylation
- Lung Development
- Spermatogenesis
- Cell Proliferation
- Menopause
- Decidualization
- Prolactin Secretion
- Transport
- Tricarboxylic Acid Cycle
- Gene Silencing
PTMs
- Methylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/HSD17B2
bosterbio.com/bosterbio-gene-info-cards/HSD17B2
References
PMID: 8099587 by Wu L., et al. Expression cloning and characterization of human 17 beta- hydroxysteroid dehydrogenase type 2, a microsomal enzyme possessing 20 alpha-hydroxysteroid dehydrogenase activity.
PMID: 7546291 by Labrie Y., et al. The human type II 17 beta-hydroxysteroid dehydrogenase gene encodes two alternatively spliced mRNA species.