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- Table of Contents
Designing a Western blot for HSP90AB1? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the HSP90AB1 Western Blot Guide2 Citations
Facts about Heat shock protein HSP 90-beta.
This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that govern its substrate recognition, ATPase cycle and chaperone function (PubMed:16478993, PubMed:19696785).
| Human | |
|---|---|
| Gene Name: | HSP90AB1 |
| Uniprot: | P08238 |
| Entrez: | 3326 |

| Belongs to: |
|---|
| heat shock protein 90 family |

D6S182; Heat shock 84 kDa; heat shock 90kD protein 1, beta; heat shock 90kDa protein 1, beta; heat shock protein 90kDa alpha (cytosolic), class B member 1; heat shock protein beta; heat shock protein HSP 90-beta; HSP 84; HSP84; HSP90 beta; HSP90AB1; HSP90B; HSP90-BETA; HSP90BHSP 90; HSPC2; HSPC2D6S182; HSPCB; HSPCBFLJ26984
Mass (kDA):
83.264 kDA

| Human | |
|---|---|
| Location: | 6p21.1 |
| Sequence: | 6; NC_000006.12 (44246166..44253888) |
Cytoplasm. Melanosome. Nucleus. Secreted. Cell membrane. Identified by mass spectrometry in melanosome fractions from stage I to stage IV (PubMed:17081065). Translocates with BIRC2 from the nucleus to the cytoplasm during differentiation (PubMed:18239673). Secreted when associated with TGFB1 processed form (LAP) (PubMed:20599762).




PMID: 3301534 by Rebbe N.F., et al. Nucleotide sequence of a cDNA for a member of the human 90-kDa heat- shock protein family.
PMID: 2768249 by Rebbe N.F., et al. Nucleotide sequence and regulation of a human 90-kDa heat shock protein gene.
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