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- Table of Contents
Endoplasmin Antibodies
AND HSP90B1 ELISA kits, Endoplasmin Proteins
Many biological assays use antibodies to detect Endoplasmin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Endoplasmin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Endoplasmin antibodies...
Designing a Western blot for Endoplasmin? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the HSP90B1 Western Blot GuideHSP90B1 Infographic by Boster Bio
All HSP90B1 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # PB9637
100 μg/vial
Cat # PB9637
100 μg/vial
Anti-GRP94/HSP90B1 Antibody Picoband®
1 Citations
Human, Rat
IHC, IHC-F, ICC, WB
$370
Cat # PA1340
100 μg/vial
Cat # PA1340
100 μg/vial
Anti-GRP94 HSP90B1 Rabbit Monoclonal Antibody
1 Citations
Human, Mouse
IF, IHC, ICC, WB
$370
Cat # M02393-1
100 μl
Cat # M02393-1
100 μl
HSP90B1 Overview
Facts about Endoplasmin.
Endoplasmin (HSP90B1)
Molecular chaperone that functions in the processing and transport of secreted proteins. When associated with CNPY3, required for proper folding of Toll-like receptors (By similarity).
Functions in endoplasmic reticulum associated degradation (ERAD). Has ATPase activity.
Gene Information
| Human | |
|---|---|
| Gene Name: | HSP90B1 |
| Uniprot: | P14625 |
| Entrez: | 7184 |
Family
| Belongs to: |
|---|
| heat shock protein 90 family |
Alternative Names
94 kDa glucose-regulated protein; ECGP; Endoplasmin; endothelial cell (HBMEC) glycoprotein; glucose regulated protein, 94 kDa; gp96; GP96ECGP; Grp94; GRP-94; GRP94gp96 homolog; Heat shock protein 90 kDa beta member 1; heat shock protein 90kDa beta (Grp94), member 1; HSP90B1; TRA1endoplasmin; tumor rejection antigen (gp96) 1; Tumor rejection antigen 1; Tumor rejection antigen-1 (gp96)
Molecular Weight
Mass (kDA):
92.469 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 12q23.3 |
| Sequence: | 12; NC_000012.12 (103930410..103947926) |
Subcellular Localizations
Endoplasmic reticulum lumen. Sarcoplasmic reticulum lumen. Melanosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
Diseases
- Malignant Neoplasms
- Endoplasmic Reticulum Stress
- Neoplasms
- Bipolar Disorder
- Neoplasm Metastasis
- Metastatic Malignant Neoplasm To The Lymph Node
- Malignant Neoplasm Of Breast
- Infectious Mononucleosis
- Neurodegenerative Disorders
- Bernard-soulier Syndrome
- Carcinoma
- Multiple Myeloma
- Hemorrhage
Interacting Proteins
- ERBB2
- FANCC
- HSPA5
Pathways
- Protein Folding
- Fertilization
- Transport
- Germinal Center Formation
- Secretory Pathway
- Cell Proliferation
- Meiosis Ii
- Mitosis
- Platelet Activation
- Plasma Cell Differentiation
- Oocyte Maturation
- Response To Heat
PTMs
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/HSP90B1
bosterbio.com/bosterbio-gene-info-cards/HSP90B1
References
PMID: 2377606 by Maki R.G., et al. Human homologue of murine tumor rejection antigen gp96: 5'-regulatory and coding regions and relationship to stress-induced proteins.
PMID: 2546060 by Chang S.C., et al. Glucose-regulated protein (GRP94 and GRP78) genes share common regulatory domains and are coordinately regulated by common trans- acting factors.
1 Publications of Boster Endoplasmin Antibodies & ELISA Kits
- PubMed ID: 27738755, Ibutilide protects against cardiomyocytes injury via inhibiting endoplasmic reti...
*More publications can be found for each product on its corresponding product page