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- Table of Contents
HSPD1 Antibodies
AND HSPD1 ELISA kits, HSPD1 Proteins
Many biological assays use antibodies to detect HSPD1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with HSPD1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop HSPD1 antibodies...
Designing a Western blot for HSPD1? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the HSPD1 Western Blot GuideHSPD1 Infographic by Boster Bio
All HSPD1 Products
Product
Figures
Specificity
Applications
Price
Anti-HSP60/HSPD1 Antibody Picoband®
6 Citations
Human, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # PA1106
100 μg/vial
Cat # PA1106
100 μg/vial
Anti-Hsp60/HSPD1 Antibody Picoband®
3 Citations
Human, Mouse, Rat
IF, IHC, ICC, WB
$370
Cat # PB9337
100 μg/vial
Cat # PB9337
100 μg/vial
Human, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M01280-3
100 μg/vial
Cat # M01280-3
100 μg/vial
Zebrafish
IF, IHC, WB
$470
Cat # AZQ803B0
100 μg/vial
Cat # AZQ803B0
100 μg/vial
Human, Mouse, Rat
ELISA, IP, IF, IHC, WB
$146
Cat # M01280-6
20μL, 40μL, 100μL, 200μL
Cat # M01280-6
20μL, 40μL, 100μL, 200μL
HSPD1 Overview
Facts about 60 kDa heat shock protein, mitochondrial.
60 kDa heat shock protein, mitochondrial (HSPD1)
Together with Hsp10, eases the correct folding of imported proteins. May also prevent misfolding and promote the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matrix (PubMed:1346131, PubMed:11422376).
The functional units of these chaperonins consist of heptameric rings of the large subunit Hsp60, which serve as a back-to-back double ring. In a cyclic reaction, Hsp60 ring complexes bind one unfolded substrate protein per ring, followed by the binding of ATP and institution with 2 heptameric rings of the co-chaperonin Hsp10.
Gene Information
| Human | |
|---|---|
| Gene Name: | HSPD1 |
| Uniprot: | P10809 |
| Entrez: | 3329 |
Family
| Belongs to: |
|---|
| chaperonin (HSP60) family |
Alternative Names
60 kDa chaperonin; Chaperonin 60; cpn60; GROEL; heat shock 60kD protein 1 (chaperonin); heat shock 60kDa protein 1 (chaperonin); Heat shock protein 60; heat shock protein 65; HLD4; HSP60; HSP-60; HSP60SPG13; HSP65; HSPD1; HuCHA60; Mitochondrial matrix protein P1,60 kDa heat shock protein, mitochondrial; P60 lymphocyte protein; short heat shock protein 60 Hsp60s1; spastic paraplegia 13 (autosomal dominant); SPG13
Molecular Weight
Mass (kDA):
61.055 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 2q33.1 |
| Sequence: | 2; NC_000002.12 (197486584..197500274, complement) |
Subcellular Localizations
Mitochondrion matrix.
Diseases
- Neoplasms
- Malignant Neoplasms
- Paraplegia
- Spastic Paraplegia
- Spastic Paraplegia, Hereditary
- Inflammation
- Neurodegenerative Disorders
- Hyperplasia
- Carcinoma
- Nerve Degeneration
- Leukodystrophy
- Pelizaeus-merzbacher Disease
Interacting Proteins
- BCAT2
- BRCA1
- CEP70
- DARS2
- KRT31
- KRT40
- KRTAP10-8
- KRTAP5-9
- LZTS2
- MFHAS1
Pathways
- Pathogenesis
- Cell Cycle
- Cell Proliferation
- Spermatogenesis
- Protein Folding
- Transport
- Fertilization
- Immune Response
- Cell Death
- Cell Growth
- Exocytosis
- Regeneration
- Acrosome Reaction
PTMs
- Phosphorylation
- Biotinylation
- Glycosylation
Research Areas
- Apoptosis
- Cellular Markers
- Loading Controls
- Membrane Trafficking and Chaperones
- Mitochondrial Markers
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/HSPD1
bosterbio.com/bosterbio-gene-info-cards/HSPD1
References
PMID: 2568584 by Jindal S., et al. Primary structure of a human mitochondrial protein homologous to the bacterial and plant chaperonins and to the 65-kilodalton mycobacterial antigen.
PMID: 1980192 by Venner T.J., et al. Nucleotide sequences and novel structural features of human and Chinese hamster hsp60 (chaperonin) gene families.
7 Publications of Boster HSPD1 Antibodies & ELISA Kits
- PubMed ID: , Denatured corona proteins mediate the intracellular bioactivities of nanoparticl...
- PubMed ID: 27698781, Expression and location of HSP60 and HSP10 in the heart tissue of heat-stressed ...
- PubMed ID: 24735884, Hepatic mitochondrial and ER stress induced by defective PPAR? signaling in the ...
- PubMed ID: 20673188, Cui Yd, Du Yz, Lu Mx, Qiang Ck. J Insect Sci. 2010;10:100. Doi: 10.1673/031.010....
- PubMed ID: 22500017, Hager L, Li L, Pun H, Liu L, Hossain Ma, Maguire Gf, Naples M, Baker C, Magomedo...
- PubMed ID: 24257806, Li L, Nan P, Zhai S, Wang L, Si S, Chang Z. Mol Cell Biochem. 2014 Feb;387(1-2):...
- PubMed ID: 24380831, Li L, Zhai S, Wang L, Si S, Wu H, Chang Z. Fish Shellfish Immunol. 2014 Feb;36(2...
*More publications can be found for each product on its corresponding product page