Hvcn1 Antibodies

AND Hvcn1 ELISA kits, Hvcn1 Proteins

Many biological assays use antibodies to detect Hvcn1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Hvcn1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Hvcn1 antibodies...

We validate the specificity of these antibodies to Hvcn1 by testing them on tissues known to express Hvcn1 positively and negatively. Browse below to find the Hvcn1 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing an IHC experiment for Hvcn1? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the HVCN1 IHC Guide

Hvcn1 Infographic by Boster Bio

All Hvcn1 Products

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Specificity

Applications

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Anti-HVCN1 Antibody

Western blot analysis of HVCN1 in (A) human spleen and (B) mouse spleen tissue lysates with HVCN1 antibody at 1 μg/mL

Immunohistochemistry of HVCN1 in rat spleen tissue with HVCN1 antibody at 5 μg/mL

Immunofluorescence of HVCN1 in Rat Spleen cells with HVCN1 antibody at 20 μg/mL

Human, Mouse, Rat

ELISA, IF, IHC-P, WB

$481
Cat # A05922
0.1 mg

HVCN1 (NM_001040107) Human Over-expression Lysate

HVCN1 Human Over-expression Lysates NM_001040107

Human

$628
Cat # LS084329
20 µg, 100 µg

Anti-HVCN1 Antibody Picoband®

Western blot analysis of HVCN1 using anti-HVCN1 antibody (A05922-1)

IHC analysis of HVCN1 using anti-HVCN1 antibody (A05922-1)

Human

ELISA, IHC, WB

$370
Cat # A05922-1
100 μg/vial

Hvcn1 Overview

Facts about Voltage-gated hydrogen channel 1.

Voltage-gated hydrogen channel 1 (Hvcn1)

Mediates the voltage-dependent proton permeability of excitable membranes. Types a proton-selective channel through which protons can pass in accordance with their electrochemical gradient.

Proton efflux, accompanied by membrane depolarization, facilitates acute production of reactive oxygen species in phagocytosis. .

Gene Information

Mouse
Gene Name:	Hvcn1
Uniprot:	Q3U2S8
Entrez:	74096

Family

Belongs to:

hydrogen channel family

Alternative Names

hydrogen voltage-gated channel 1; VSOP

Molecular Weight

Mass (kDA):
31.242 kDA

Genomic Context


Mouse

Location:	5\|5 F
Sequence:	5;

Tissue Specificity

Enriched in immune tissues, such as bone marrow, macrophages and spleen.

Diseases

Chronic Sinusitis
Infective Disorder
Nasal Polyps
Rhinorrhea
B-cell Lymphomas
Malignant Paraganglionic Neoplasm
Autoimmune Reaction
Malignant Neoplasms
Sinusitis
Asthma

Lymphoma
Eosinophilia
Chronic Lymphocytic Leukemia
Malignant Lymphoma, Lymphocytic, Intermediate Differentiation, Diffuse

Pathways

Secretion
Acid Secretion
Histamine Secretion
Cell Activation
Phagocytosis
Sperm Capacitation
Respiratory Burst

B Cell Activation
Glycolysis

PTMs

Phosphorylation

Oxidation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Hvcn1

References

PMID: 16556803 by Sasaki M., et al. A voltage sensor-domain protein is a voltage-gated proton channel.

PMID: 19805063 by Morgan D., et al. Voltage-gated proton channels maintain pH in human neutrophils during phagocytosis.