HMGA2 Antibodies

AND HMGA2 ELISA kits, HMGA2 Proteins

Many biological assays use antibodies to detect HMGA2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with HMGA2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop HMGA2 antibodies...

We validate the specificity of these antibodies to HMGA2 by testing them on tissues known to express HMGA2 positively and negatively. Browse below to find the HMGA2 antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing a Western blot for HMGA2? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.

Open the HMGA2 Western Blot Guide

Designing an IHC experiment for HMGA2? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the HMGA2 IHC Guide

HMGA2 Infographic by Boster Bio

All HMGA2 Products

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Product

Figures

Specificity

Applications

Price

Anti-HMGA2 Antibody

IHC analysis of HMGA2 using anti-HMGA2 antibody (A00436-3)

IF analysis of HMGA2 using anti-HMGA2 antibody (A00436-3)

Human, Mouse, Rat

ELISA, IP, IF, IHC, ICC, WB

$370
Cat # A00436-3
100 μl/vial

Anti-Mouse Hmga2 Antibody (C-term)

Fluorescent image of C2C12cells stained with Mouse Hmga2 Antibody (C-term)

Western blot analysis of lysates from HepG2, NCCIT, mouse NIH/3T3, mouse F9 cell line (from left to right), using Hmga2 Antibody (C-term)

Human, Mouse

IF, WB

$299
Cat # A00436-2
80 µl

HMGA2 (NM_003483) Human Over-expression Lysate

HMGA2 Human Over-expression Lysates NM_003483

Human

$628
Cat # LS008091
20 µg, 100 µg

Anti-HMGA2 Antibody (C-term)

HMGA2 Antibody (C-term) western blot analysis in HepG2 cell line lysates (35ug/lane)

Human

Flow Cytometry, WB

$299
Cat # A00436-1
80 µl

HMGA2 (NM_003484) Human Recombinant Protein

Coomassie blue staining of purified HMGA2 protein

$1062
Cat # PROTP52926
20 µg

HMGA2 Overview

Facts about High mobility group protein HMGI-C.

HMGA2 3D structure. Source: alphafold

High mobility group protein HMGI-C (HMGA2)

Functions as a transcriptional regulator. Functions in cell cycle regulation through CCNA2.

Plays an important role in chromosome condensation during the meiotic G2/M transition of spermatocytes. Plays a role in postnatal myogenesis, is involved in satellite cell activation (By similarity).

Gene Information

Human
Gene Name:	HMGA2
Uniprot:	P52926
Entrez:	8091

Family

Belongs to:

HMGA family

Alternative Names

BABL; BABLHMGI-C; high mobility group AT-hook 2; High mobility group AT-hook protein 2; high mobility group protein HMGI-C; high-mobility group (nonhistone chromosomal) protein isoform I-C; High-mobility group protein HMGI-C; HMGA2; HMGIC; HMGICSTQTL9; LIPO

Molecular Weight

Mass (kDA):
11.832 kDA

Genomic Context


Human

Location:	12q14.3
Sequence:	12; NC_000012.12 (65824460..65966291)

Subcellular Localizations

Nucleus.

Diseases

Neoplasms
Malignant Neoplasms
Cell Transformation, Neoplastic
Malignant Paraganglionic Neoplasm
Lipoma
Carcinoma
Adenoma
Uterine Fibroids
Fibroid Tumor
Uterine Neoplasms
Chromosomal Translocation
Cytogenetic Abnormality
Neoplasm Metastasis

Benign Neoplasm
Liposarcoma
Mixed Salivary Gland Tumor
Hamartoma
Lung Neoplasms
Pituitary Diseases
Pituitary Neoplasms

Interacting Proteins

PRMT6

Pathways

Cell Proliferation
Pathogenesis
Cell Growth
Cell Cycle
Oncogenesis
Senescence
Cellular Senescence
Cell Differentiation
Translation
Interphase
Gene Silencing
Metaphase
Rna Interference

Aging
Methylation
Dna Repair
Regulation Of Gene Expression
Spermatogenesis
Reverse Transcription
Chromatin Organization

PTMs

Phosphorylation
Acetylation
Methylation

Sumoylation
Cleavage
Glycosylation

Research Areas

Cancer

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/HMGA2

References

PMID: 8198613 by Patel U.A., et al. Expression and cDNA cloning of human HMGI-C phosphoprotein.

PMID: 7670494 by Schoenmakers E.F.P.M., et al. Recurrent rearrangements in the high mobility group protein gene, HMGI-C, in benign mesenchymal tumours.