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- Table of Contents
Heme oxygenase 1 Antibodies
AND HMOX1 ELISA kits, Heme oxygenase 1 Proteins
Many biological assays use antibodies to detect Heme oxygenase 1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Heme oxygenase 1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Heme oxygenase 1 antibodies...
Designing a Western blot for Heme oxygenase 1? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the HMOX1 Western Blot GuideHMOX1 Infographic by Boster Bio
All HMOX1 Products
Product
Figures
Specificity
Applications
Price
Anti-Heme Oxygenase 1/HMOX1 Antibody Picoband®
41 Citations
Mouse, Rat
IHC, WB
$370
Cat # PB9085
100 μg/vial
Cat # PB9085
100 μg/vial
Human, Mouse
Flow Cytometry, IP, IHC, WB
$370
Cat # M00253
100 μl
Cat # M00253
100 μl
Human HO-1/HMOX1/HSP32 ELISA Kit PicoKine®
3 Citations
Human
ELISA
$499
Cat # EK0888
96 wells/kit, with removable strips.
Cat # EK0888
96 wells/kit, with removable strips.
Anti-Heme Oxygenase 1/HMOX1 Antibody Picoband®
6 Citations
Human
IHC, WB
$370
Cat # PB9212
100 μg/vial
Cat # PB9212
100 μg/vial
Anti-Heme Oxygenase 1/Hmox1 Antibody Picoband®
5 Citations
Rat
ELISA, WB
$370
Cat # A00253-1
100 μg/vial
Cat # A00253-1
100 μg/vial
Anti-Heme Oxygenase 1/HMOX1 Antibody Picoband®
1 Citations
Human
ELISA, Flow Cytometry, WB
$370
Cat # A00253-2
100 μg/vial
Cat # A00253-2
100 μg/vial
Human, Mouse, Rat
ELISA, IP, IF, IHC, WB
$146
Cat # M00253-3
20μL, 40μL, 100μL, 200μL
Cat # M00253-3
20μL, 40μL, 100μL, 200μL
Human
$628
Cat # LS003162
20 µg, 100 µg
Cat # LS003162
20 µg, 100 µg
HMOX1 Overview
Facts about Heme oxygenase 1.
Heme oxygenase 1 (HMOX1)
Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase.
Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed. Exhibits cytoprotective effects since excess of free heme sensitizes cells to undergo apoptosis.
Gene Information
| Human | |
|---|---|
| Gene Name: | HMOX1 |
| Uniprot: | P09601 |
| Entrez: | 3162 |
Family
| Belongs to: |
|---|
| heme oxygenase family |
Alternative Names
bK286B10; EC 1.14.99.3; heat shock protein, 32-kD; heme oxygenase (decycling) 1; HMOX1; HO; HO1; HO-1; HO-1heme oxygenase 1; HSP32
Molecular Weight
Mass (kDA):
32.819 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 22q12.3 |
| Sequence: | 22; NC_000022.11 (35381096..35394207) |
Tissue Specificity
Expressed at higher levels in renal cancer tissue than in normal tissue (at protein level).
Subcellular Localizations
Microsome. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side.
Diseases
- Inflammation
- Malignant Neoplasms
- Ischemia
- Reperfusion Injury
- Neoplasms
- Hypoxia
- Hypertensive Disease
- Inflammatory Response
- Fibrosis
- Atherosclerosis
- Tumor Angiogenesis
- Infarction
- Diabetes Mellitus
Interacting Proteins
- POT1
Pathways
- Cell Death
- Pathogenesis
- Cell Proliferation
- Inflammatory Response
- Angiogenesis
- Localization
- Cell Cycle
- Aging
- Transport
- Secretion
- Response To Oxidative Stress
- Neuroprotection
- Cell Growth
PTMs
- Phosphorylation
- Oxidation
- Cleavage
- Reduction
- Nitration
- Methylation
- Ubiquitination
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/HMOX1
bosterbio.com/bosterbio-gene-info-cards/HMOX1
References
PMID: 3345742 by Yoshida T., et al. Human heme oxygenase cDNA and induction of its mRNA by hemin.
PMID: 2911585 by Keyse S.M., et al. Heme oxygenase is the major 32-kDa stress protein induced in human skin fibroblasts by UVA radiation, hydrogen peroxide, and sodium arsenite.
38 Publications of Boster Heme oxygenase 1 Antibodies & ELISA Kits
- PubMed ID: 10.3892/etm.2020.8605, Inactivated pseudomonas aeruginosa protects against myocardial ischemia reperfu...
- PubMed ID: 10.3390/antiox8050119, Phytochemical Combination PB125 Activates the Nrf2 Pathway and Induces Cellular ...
- PubMed ID: 10.1155/2021/6103158, Rhodiola rosea L. Attenuates Cigarette Smoke and Lipopolysaccharide-Induced COPD...
- PubMed ID: 10.1155/2016/1591803, Effect of Blueberry Anthocyanins Malvidin and Glycosides on the Antioxidant Prop...
- PubMed ID: 10.1111/1750-3841.13706, Quercetin, Hyperin, and Chlorogenic Acid Improve Endothelial Function by Antioxi...
- PubMed ID: 10.1039/C6FO00419A, Myricetin ameliorates brain injury and neurological deficits via Nrf2 activation...
- PubMed ID: 10.1021/acs.jafc.0c07046, Polyphenol-Rich Extract from Litchi chinensis Seeds Alleviates Hypertension-Indu...
- PubMed ID: 10.1016/j.lfs.2020.117292, Nifedipine inhibits oxidative stress and ameliorates osteoarthritis by activatin...
- PubMed ID: 10.1016/j.jep.2018.01.033, Improvement of Cisplatin-induced renal dysfunction by Schisandra chinensis stems...
- PubMed ID: 10.1016/j.ejphar.2021.174629, Fucoxanthin regulates Nrf2 signaling to decrease oxidative stress and improves r...
- PubMed ID: 10.1007/s11596-009-0118-0, Heme oxygenase-1 expression in rats with acute lung rejection and implication
- PubMed ID: 34082111, Dong H,Hao L,Zhang W,Zhong W,Guo W,Yue R,Sun X,Zhou Z.Activation of AhR-NQO1 sig...
- PubMed ID: -, Huanyue Cui,Xueying Liu,Jin Zhang,Ke Zhang,Dahong Yao,Shi Dong,Shushu Feng,Lu Ya...
- PubMed ID: 33508367, Sun S,Zhang J,Li H,Du Y,Li S,Li A,Suo X,Wang Y,Sun Q.Anti-inflammatory activity ...
- PubMed ID: 33359640, Li D,Bai X,Jiang Y,Cheng Y.Butyrate alleviates PTZ-induced mitochondrial dysfunc...
- PubMed ID: 33355514, Sun S,Wang Y,Du Y,Sun Q,He L,Zhu E,Li J. Oxidative stress-mediated hepatotoxicit...
- PubMed ID: 31933966, Protective effects of hydrogen-rich saline against renal ischemia-reperfusion in...
- PubMed ID: 19477871, Role of heme oxygenase-1/carbon monoxide system in pulmonary ischemia-reperfusio...
- PubMed ID: 29867499, The Natural Flavone Acacetin Confers Cardiomyocyte Protection Against Hypoxia/Re...
- PubMed ID: 29033843, The apolipoprotein A?I mimetic peptide, D?4F, restrains neointimal formation thr...
- PubMed ID: 26798657, Heme Oxygenase-1 Promotes Delayed Wound Healing in Diabetic Rats
*Showing only the more recent 20. More publications can be found for each product on its corresponding product page