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- Table of Contents
IDH2 Antibodies
AND IDH2 ELISA kits, IDH2 Proteins
Many biological assays use antibodies to detect IDH2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with IDH2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop IDH2 antibodies...
Designing a Western blot for IDH2? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the IDH2 Western Blot GuideIDH2 Infographic by Boster Bio
All IDH2 Products
Product
Figures
Specificity
Applications
Price
Anti-IDH2 Antibody Picoband®
4 Citations
Human, Mouse, Rat
IF, IHC, ICC, WB
$370
Cat # PB9602
100 μg/vial
Cat # PB9602
100 μg/vial
Human, Mouse, Rat
IHC, WB
$370
Cat # M00510-3
100 μg/vial
Cat # M00510-3
100 μg/vial
Human, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M00510-4
100 μg/vial
Cat # M00510-4
100 μg/vial
Human, Mouse, Rat
Flow Cytometry, IF, ICC, WB
$370
Cat # M00510-2
100 μg/vial
Cat # M00510-2
100 μg/vial
IDH2 Overview
Facts about Isocitrate dehydrogenase [NADP], mitochondrial.
Isocitrate dehydrogenase [NADP], mitochondrial (IDH2)
Plays a role in intermediary metabolism and energy production. It might closely associate or interact with the pyruvate dehydrogenase complex.
.
Gene Information
| Human | |
|---|---|
| Gene Name: | IDH2 |
| Uniprot: | P48735 |
| Entrez: | 3418 |
Family
| Belongs to: |
|---|
| isocitrate and isopropylmalate dehydrogenases family |
Alternative Names
D2HGA2; EC 1.1.1.42; ICD-M; IDH; IDHM; IDP; IDPM; isocitrate dehydrogenase [NADP], mitochondrial; isocitrate dehydrogenase 2 (NADP+), mitochondrial; mNADP-IDH; NADP(+)-specific ICDH; Oxalosuccinate decarboxylase
Molecular Weight
Mass (kDA):
50.909 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 15q26.1 |
| Sequence: | 15; NC_000015.10 (90083045..90102468, complement) |
Subcellular Localizations
Mitochondrion.
Diseases
- Neoplasms
- Glioma
- Leukemia
- Myeloid Leukemia
- Brain Neoplasms
- Leukemia, Myelocytic, Acute
- Malignant Neoplasms
- Glioblastoma
- Astrocytoma
- Oligodendroglioma
- Cell Transformation, Neoplastic
- Dysmyelopoietic Syndromes
- Malignant Paraganglionic Neoplasm
Pathways
- Methylation
- Pathogenesis
- Dna Methylation
- Tricarboxylic Acid Cycle
- Demethylation
- Glycolysis
- Histone Demethylation
- Localization
- Cell Growth
- Angiogenesis
- Dna Hypermethylation
- Oxidative Phosphorylation
- Histone Methylation
PTMs
- Methylation
- Demethylation
- Decarboxylation
- Carboxylation
- Reduction
- Deacetylation
Research Areas
- Epigenetics
- Hypoxia
- Lipid and Metabolism
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/IDH2
bosterbio.com/bosterbio-gene-info-cards/IDH2
References
PMID: 22416140 by Yu W., et al. SIRT3 protein deacetylates isocitrate dehydrogenase 2 (IDH2) and regulates mitochondrial redox status.
PMID: 19228619 by Yan H., et al. IDH1 and IDH2 mutations in gliomas.