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- Table of Contents
IRF2 Antibodies
AND IRF2 ELISA kits, IRF2 Proteins
Many biological assays use antibodies to detect IRF2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with IRF2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop IRF2 antibodies...
Designing a Western blot for IRF2? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the IRF2 Western Blot GuideIRF2 Infographic by Boster Bio
All IRF2 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
ELISA, Flow Cytometry, IP, IF, IHC, ICC, WB
$370
Cat # A11406-2
100 μg/vial
Cat # A11406-2
100 μg/vial
Human
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A10706
100 μg/vial
Cat # A10706
100 μg/vial
Human, Mouse, Rat
WB
$370
Cat # PA1818
100 μg/vial
Cat # PA1818
100 μg/vial
Human, Mouse, Rat
IHC, WB
$523
Cat # M11406
100 µl
Cat # M11406
100 µl
Human, Mouse, Rat
ELISA
$480
Cat # EKC1678
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1678
1 kit, containing one 96-well plate and all necessary reagents
IRF2 Overview
Facts about Interferon regulatory factor 2.
Interferon regulatory factor 2 (IRF2)
Specifically binds to the upstream regulatory region of type I IFN and IFN-inducible MHC class I genes (the interferon consensus sequence (ICS)) and represses these genes. Also acts as an activator for several genes such as H4 and IL7.
Constitutively binds to the ISRE promoter to activate IL7. Involved in cell cycle regulation through binding the site II (HiNF-M) promoter region of H4 and activating transcription during cell growth.
Gene Information
| Human | |
|---|---|
| Gene Name: | IRF2 |
| Uniprot: | P14316 |
| Entrez: | 3660 |
Family
| Belongs to: |
|---|
| IRF family |
Alternative Names
DKFZp686F0244; interferon regulatory factor 2; IRF2; IRF-2
Molecular Weight
Mass (kDA):
39.354 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 4q35.1 |
| Sequence: | 4; NC_000004.12 (184382741..184474580, complement) |
Tissue Specificity
Expressed throughout the epithelium of the colon. Also expressed in lamina propria.
Subcellular Localizations
Nucleus.
Diseases
- Neoplasms
- Virus Diseases
- Malignant Neoplasms
- Leukemia
- Myeloid Leukemia
- Cell Transformation, Neoplastic
- Carcinoma
- Leukemia, Myelocytic, Acute
- Inflammation
- Infective Disorder
- Dermatologic Disorders
- Endometrial Polyp
- Malignant Neoplasm Of Breast
Interacting Proteins
- ATG7
- FOXK1
- FOXK2
- PPP3CB
Pathways
- Cell Growth
- Cell Cycle
- Immune Response
- Cell Development
- Localization
- Cell Differentiation
- Oncogenesis
- Cell Death
- S Phase
- Pathogenesis
- Regulation Of Cell Growth
- Viral Replication
- Cell Proliferation
PTMs
- Phosphorylation
- Acetylation
- Cleavage
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/IRF2
bosterbio.com/bosterbio-gene-info-cards/IRF2
References
PMID: 2813069 by Itoh S., et al. Sequence of a cDNA coding for human IRF-2.
PMID: 8106512 by Cha Y., et al. Human interferon regulatory factor 2 gene. Intron-exon organization and functional analysis of 5'-flanking region.