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- Table of Contents
IRF4 Antibodies
AND IRF4 ELISA kits, IRF4 Proteins
Many biological assays use antibodies to detect IRF4, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with IRF4 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop IRF4 antibodies...
Designing a Western blot for IRF4? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the IRF4 Western Blot GuideIRF4 Infographic by Boster Bio
All IRF4 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
ELISA, IF, ICC, WB
$481
Cat # A00401
0.1 mg
Cat # A00401
0.1 mg
Human, Mouse
ELISA
$480
Cat # EKC1819
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1819
1 kit, containing one 96-well plate and all necessary reagents
IRF4 Overview
Facts about Interferon regulatory factor 4.
Interferon regulatory factor 4 (IRF4)
Transcriptional activator. Binds to the interferon- stimulated response element (ISRE) of the MHC class I promoter.
Binds the immunoglobulin lambda light chain enhancer, together with PU.1.
Gene Information
| Human | |
|---|---|
| Gene Name: | IRF4 |
| Uniprot: | Q15306 |
| Entrez: | 3662 |
Family
| Belongs to: |
|---|
| IRF family |
Alternative Names
interferon regulatory factor 4; IRF4; IRF-4; LSIRF; LSIRFMUM1; Lymphocyte-specific interferon regulatory factor; Multiple myeloma oncogene 1; MUM1; NF-EM5
Molecular Weight
Mass (kDA):
51.772 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 6p25.3 |
| Sequence: | 6; NC_000006.12 (391752..411443) |
Tissue Specificity
Lymphoid cells.
Subcellular Localizations
Nucleus.
Diseases
- Lymphoma
- B-cell Lymphomas
- Diffuse Large B-cell Lymphoma
- Neoplasms
- Multiple Myeloma
- Malignant Neoplasms
- Leukemia
- Chromosomal Translocation
- Hodgkin Disease
- Malignant Paraganglionic Neoplasm
- Inflammation
- Lymphoma, Follicular
- Chronic Lymphocytic Leukemia
Interacting Proteins
- ELP1
- IRAK1
- TLK2
- YTHDC2
Pathways
- Cell Differentiation
- Pathogenesis
- Plasma Cell Differentiation
- Immune Response
- Cell Development
- Cell Cycle
- Secretion
- Cell Proliferation
- Pigmentation
- Cytokine Production
- Interphase
- Cell Maturation
- Oncogenesis
PTMs
- Phosphorylation
- Methylation
- Acetylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/IRF4
bosterbio.com/bosterbio-gene-info-cards/IRF4
References
PMID: 8921401 by Grossman A., et al. Cloning of human lymphocyte-specific interferon regulatory factor (hLSIRF/hIRF4) and mapping of the gene to 6p23-p25.
PMID: 9326949 by Iida S., et al. Deregulation of MUM1/IRF4 by chromosomal translocation in multiple myeloma.
1 Publications of Boster IRF4 Antibodies & ELISA Kits
- PubMed ID: 10.3892/or.2016.4562, TIPE2, a negative regulator of TLR signaling, regulates p27 through IRF4-induced...
*More publications can be found for each product on its corresponding product page