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- Table of Contents
Integrin alpha-E Antibodies
AND ITGAE ELISA kits, Integrin alpha-E Proteins
Many biological assays use antibodies to detect Integrin alpha-E, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Integrin alpha-E in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Integrin alpha-E antibodies...
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ITGAE Infographic by Boster Bio
All ITGAE Products
Product
Figures
Specificity
Applications
Price
Anti-Integrin alpha E ITGAE Rabbit Monoclonal Antibody
3 Citations 7 Q&As
Human
IHC
$370
Cat # M07091
100 μl
Cat # M07091
100 μl
Human, Primate
Flow Cytometry, IP, IHC-F, WB
$299
Cat # M07091-1
0.1 mg
Cat # M07091-1
0.1 mg
Human
$960
Cat # LS003682
20 µg, 100 µg
Cat # LS003682
20 µg, 100 µg
ITGAE Overview
Facts about Integrin alpha-E.
Integrin alpha-E (ITGAE)
Integrin alpha-E/beta-7 is a receptor for E-cadherin. It mediates adhesion of intra-epithelial T-lymphocytes to epithelial cell monolayers.
.
Gene Information
| Human | |
|---|---|
| Gene Name: | ITGAE |
| Uniprot: | P38570 |
| Entrez: | 3682 |
Family
| Belongs to: |
|---|
| integrin alpha chain family |
Alternative Names
antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide; CD103 antigen; CD103; HML-1 antigen; HUMINAE; Integrin alpha E; integrin alpha-E; Integrin alpha-IEL; integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alphapolypeptide); ITGAE; MGC141996; Mucosal lymphocyte 1 antigen
Molecular Weight
Mass (kDA):
130.159 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 17p13.2 |
| Sequence: | 17; NC_000017.11 (3714628..3803766, complement) |
Tissue Specificity
Expressed on a subclass of T-lymphocytes known as intra-epithelial lymphocytes which are located between mucosal epithelial cells.
Subcellular Localizations
Membrane; Single-pass type I membrane protein.
Diseases
- Tissue Adhesions
- Neoplasms
- Inflammation
- Neoplasm Metastasis
- Brain Ischemia
- Coronary Heart Disease
- Melanoma
- Tumor Progression
- Inflammatory Bowel Diseases
- Endometrial Polyp
- Neoplasm Invasiveness
- Intestinal Diseases
- Cardiovascular Diseases
Pathways
- Cell Adhesion
- Actin Cytoskeleton Organization
- Response To Stress
- Cell Proliferation
- Immune Response
- Dna Methylation
- Cell-matrix Adhesion
- Methylation
- Cytoskeleton Organization
- T Cell Differentiation
PTMs
- Cleavage on pair of basic residues
Research Areas
- Innate Immunity
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ITGAE
bosterbio.com/bosterbio-gene-info-cards/ITGAE
References
PMID: 8119947 by Shaw S.K., et al. Molecular cloning of the human mucosal lymphocyte integrin alpha E subunit. Unusual structure and restricted RNA distribution.
PMID: 10673275 by Touchman J.W., et al. The genomic region encompassing the nephropathic cystinosis gene (CTNS): complete sequencing of a 200-kb segment and discovery of a novel gene within the common cystinosis-causing deletion.
1 Publications of Boster Integrin alpha-E Antibodies & ELISA Kits
- PubMed ID: 26688104 , BAFF and its receptors involved in the inflammation progress in adjuvant induced...
*More publications can be found for each product on its corresponding product page