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- Table of Contents
Interleukin-11 Antibodies
AND IL11 ELISA kits, Interleukin-11 Proteins
Many biological assays use antibodies to detect Interleukin-11, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Interleukin-11 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Interleukin-11 antibodies...
Designing a Western blot for Interleukin-11? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the IL11 Western Blot GuideIL11 Infographic by Boster Bio
All IL11 Products
Product
Figures
Specificity
Applications
Price
Human IL-11/Interleukin-11 ELISA Kit PicoKine®
1 Citations
Human
ELISA
$499
Cat # EK0419
96 wells/kit, with removable strips.
Cat # EK0419
96 wells/kit, with removable strips.
Mouse IL-11/Interleukin-11 ELISA Kit PicoKine®
2 Citations
Mouse
ELISA
$499
Cat # EK0420
96 wells/kit, with removable strips.
Cat # EK0420
96 wells/kit, with removable strips.
Human, Mouse
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M06426
100 μl/vial
Cat # M06426
100 μl/vial
Mouse
Cell Culture
$77
Cat # PROTP47873-2
5ug,20ug,100ug
Cat # PROTP47873-2
5ug,20ug,100ug
Human
Cell Culture
$77
Cat # PROTP20809-3
5ug,20ug,100ug
Cat # PROTP20809-3
5ug,20ug,100ug
IL11 Overview
Facts about Interleukin-11.
Interleukin-11 (IL11)
Cytokine that stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells and induces megakaryocyte maturation resulting in increased platelet production (PubMed:2145578). Also promotes the proliferation of hepatocytes in response to liver damage.
Binding to its receptor formed by IL6ST and either IL11RA1 or IL11RA2 activates a signaling cascade that promotes cell proliferation (PubMed:12919066). Signaling contributes to the activation of intracellular protein kinases and the phosphorylation of STAT3.
Gene Information
| Human | |
|---|---|
| Gene Name: | IL11 |
| Uniprot: | P20809 |
| Entrez: | 3589 |
Family
| Belongs to: |
|---|
| IL-6 superfamily |
Alternative Names
Adipogenesis inhibitory factor; AGIF; AGIFoprelvekin; IL11; IL-11; IL-11Oprelvekin; interleukin 11; interleukin-11; Oprelvekin
Molecular Weight
Mass (kDA):
21.429 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 19q13.42 |
| Sequence: | 19; NC_000019.10 (55364382..55370463, complement) |
Subcellular Localizations
Secreted.
Diseases
- Malignant Neoplasms
- Neoplasms
- Endometrial Polyp
- Cell Invasion
- Inflammation
- Leukemia
- Neoplasm Metastasis
- Tissue Adhesions
- Infertility
- Malignant Neoplasm Of Breast
- Carcinoma
- Malignant Neoplasm Of Stomach
Interacting Proteins
- MAGEA11
- S100P
Pathways
- Secretion
- Decidualization
- Cell Adhesion
- Pathogenesis
- Cell Proliferation
- Inflammatory Response
- Embryo Implantation
- Cytokine Production
- Osteoblast Differentiation
- Immune Response
- Cell Differentiation
- Glycosylation
- Angiogenesis
PTMs
- Phosphorylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/IL11
bosterbio.com/bosterbio-gene-info-cards/IL11
References
PMID: 2145578 by Paul S.R., et al. Molecular cloning of a cDNA encoding interleukin 11, a stromal cell- derived lymphopoietic and hematopoietic cytokine.
PMID: 1828438 by Kawashima I., et al. Molecular cloning of cDNA encoding adipogenesis inhibitory factor and identity with interleukin-11.
3 Publications of Boster Interleukin-11 Antibodies & ELISA Kits
- PubMed ID: 10.1007/s12195-019-00606-y, Cas9 Protein Triggers Differential Expression of Inherent Genes Especially NGFR ...
- PubMed ID: 10.1002/stem.2760, The gp130 Cytokine Interleukin‐11 Regulates Engraftment of Vav1–/– Hematop...
- PubMed ID: 33291539, Gioxari A,Amerikanou C,Papada E,Zioga E,Georgoulis AD,Bamias G,Kaliora AC.Serum ...
*More publications can be found for each product on its corresponding product page