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- Table of Contents
1 Citations 4 Q&As
4 Citations 9 Q&As
Facts about Interleukin-23 receptor.
IL23 functions in innate and adaptive immunity and might take part in acute response to infection in peripheral tissues. IL23 might cause autoimmune inflammatory diseases and be important for tumorigenesis.
| Human | |
|---|---|
| Gene Name: | IL23R |
| Uniprot: | Q5VWK5 |
| Entrez: | 149233 |

| Belongs to: |
|---|
| type I cytokine receptor family |

IBD17; IL-23 R; IL-23 receptor; IL23R; IL-23R; interleukin 23 receptor; interleukin-23 receptor
Mass (kDA):
71.722 kDA

| Human | |
|---|---|
| Location: | 1p31.3 |
| Sequence: | 1; NC_000001.11 (67138639..67259979) |
Expressed by monocytes, Th1, Th0, NK and dendritic cells. Isoform 1 is specifically expressed in NK cells.
Cell membrane; Single-pass type I membrane protein.





PMID: 12023369 by Parham C., et al. A receptor for the heterodimeric cytokine IL-23 is composed of IL- 12Rbeta1 and a novel cytokine receptor subunit, IL-23R.
PMID: 16372191 by Zhang X.-Y., et al. Identification and expression analysis of alternatively spliced isoforms of human interleukin-23 receptor gene in normal lymphoid cells and selected tumor cells.
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