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- Table of Contents
IRS1 Antibodies
AND IRS1 ELISA kits, IRS1 Proteins
Many biological assays use antibodies to detect IRS1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with IRS1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop IRS1 antibodies...
Designing a Western blot for IRS1? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the IRS1 Western Blot GuideIRS1 Infographic by Boster Bio
All IRS1 Products
Product
Figures
Specificity
Applications
Price
Anti-IRS1 Antibody Picoband®
6 Citations
Human, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # PB9223
100 μg/vial
Cat # PB9223
100 μg/vial
Human
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M00268-1
100 μg/vial
Cat # M00268-1
100 μg/vial
Human, Mouse, Rat
WB
$370
Cat # PA2269
100 μg/vial
Cat # PA2269
100 μg/vial
Human, Mouse, Rat
ELISA, IF, IHC, WB
$380
Cat # A00268S636
100ul
Cat # A00268S636
100ul
Human, Monkey, Mouse, Rat
ELISA, IF, IHC, WB
$380
Cat # A00268S1101-1
100ul
Cat # A00268S1101-1
100ul
Human, Monkey, Mouse, Rat
ELISA, IF, IHC, WB
$380
Cat # A00268S307-1
100ul
Cat # A00268S307-1
100ul
Human, Mouse, Rat
ELISA
$540
Cat # EKC2590
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2590
1 kit, containing two 96-well plates and all necessary reagents
Human, Mouse, Rat
ELISA
$540
Cat # EKC2438
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2438
1 kit, containing two 96-well plates and all necessary reagents
Human, Mouse, Rat
ELISA
$540
Cat # EKC2437
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2437
1 kit, containing two 96-well plates and all necessary reagents
Human, Mouse, Rat
ELISA
$540
Cat # EKC2079
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2079
1 kit, containing two 96-well plates and all necessary reagents
Human, Mouse, Rat
ELISA
$540
Cat # EKC2049
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2049
1 kit, containing two 96-well plates and all necessary reagents
Human, Mouse, Rat
ELISA
$540
Cat # EKC2048
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2048
1 kit, containing two 96-well plates and all necessary reagents
Human, Mouse, Rat
ELISA
$540
Cat # EKC2010
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2010
1 kit, containing two 96-well plates and all necessary reagents
Human, Mouse, Rat
ELISA
$480
Cat # EKC1309
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1309
1 kit, containing one 96-well plate and all necessary reagents
IRS1 Overview
Facts about Insulin receptor substrate 1.
Insulin receptor substrate 1 (IRS1)
May mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor binds specifically to different cellular proteins containing SH2 domains like phosphatidylinositol 3-kinase p85 subunit or GRB2.
Activates phosphatidylinositol 3-kinase when bound to the regulatory p85 subunit (By similarity). .
Gene Information
| Human | |
|---|---|
| Gene Name: | IRS1 |
| Uniprot: | P35568 |
| Entrez: | 3667 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
HIRS-1; insulin receptor substrate 1; IRS1; IRS-1
Molecular Weight
Mass (kDA):
131.591 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 2q36.3 |
| Sequence: | 2; NC_000002.12 (226731317..226798790, complement) |
Diseases
- Insulin Resistance
- Diabetes Mellitus
- Diabetes Mellitus, Non-insulin-dependent
- Obesity
- Insulin Sensitivity
- Malignant Neoplasms
- Hyperinsulinism
- Neoplasms
- Hyperglycemia
- Malignant Neoplasm Of Breast
- Liver Carcinoma
- Inflammation
- Impaired Glucose Tolerance
Interacting Proteins
- BCAR3
- ERBB2
- INSR
- PABPC1
- PIK3CA
- PIK3R1
- PIK3R3
- PTPN11
Pathways
- Transport
- Glucose Transport
- Secretion
- Pathogenesis
- Cell Proliferation
- Glucose Homeostasis
- Insulin Secretion
- Cell Growth
- Localization
- Cell Cycle
- Aging
- Gluconeogenesis
- Translation
PTMs
- Phosphorylation
- Dephosphorylation
- Oxidation
- Ubiquitination
- Cleavage
- Reduction
- Nitration
- Glycosylation
- Acetylation
Research Areas
- Autophagy
- Cancer
- Diabetes Research
- mTOR Pathway
- Neuroscience
- Signal Transduction
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/IRS1
bosterbio.com/bosterbio-gene-info-cards/IRS1
References
PMID: 8513971 by Araki E., et al. Human skeletal muscle insulin receptor substrate-1. Characterization of the cDNA, gene, and chromosomal localization.
PMID: 1311924 by Nishiyama M., et al. Cloning and increased expression of an insulin receptor substrate-1- like gene in human hepatocellular carcinoma.
3 Publications of Boster IRS1 Antibodies & ELISA Kits
- PubMed ID: PMID:26550236, Vibration exercise decreases insulin resistance and modulates the insulin signal...
- PubMed ID: 10.1016/j.anireprosci.2019.05.006, Effect of maternal feed restriction in dairy goats at different stages of gestat...
- PubMed ID: 25536154, Mi L, Chen Y, Zheng X, Li Y, Zhang Q, Mo D, Yang G. J Cell Biochem. 2015 Jul;116...
*More publications can be found for each product on its corresponding product page