KIRREL2 Antibodies

AND KIRREL2 ELISA kits, KIRREL2 Proteins

Many biological assays use antibodies to detect KIRREL2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with KIRREL2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop KIRREL2 antibodies...

We validate the specificity of these antibodies to KIRREL2 by testing them on tissues known to express KIRREL2 positively and negatively. Browse below to find the KIRREL2 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing an IHC experiment for KIRREL2? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the KIRREL2 IHC Guide

KIRREL2 Infographic by Boster Bio

All KIRREL2 Products

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Specificity

Applications

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Anti-Kin of IRRE-like protein 2 KIRREL2 Antibody

Western blot analysis of KIRREL2 in 293 cell lysate with KIRREL2 antibody at 1 μg/ml in (A) the absence and (B) the presence of blocking peptide

Immunohistochemistry of KIRREL2 in human pancreas tissue with KIRREL2 antibody at 5 μg/ml

Immunofluorescence of KIRREL2 in human pancreas tissue with KIRREL2 antibody at 20 μg/ml

Human, Mouse, Rat

ELISA, IF, IHC-P, WB

$481
Cat # A07812
0.1 mg

KIRREL2 (NM_032123) Human Over-expression Lysate

KIRREL2 Human Over-expression Lysates NM_032123

Human

$960
Cat # LS084063
20 µg, 100 µg

KIRREL2 Overview

Facts about Kin of IRRE-like protein 2.

KIRREL2 3D structure. Source: alphafold

Kin of IRRE-like protein 2 (KIRREL2)

May regulate basal insulin secretion. .

Gene Information

Human
Gene Name:	KIRREL2
Uniprot:	Q6UWL6
Entrez:	84063

Family

Belongs to:

immunoglobulin superfamily

Alternative Names

DKFZp564A1164; Filtrin; FILTRINkin of IRRE-like protein 2; kin of IRRE like 2 (Drosophila); Kin of irregular chiasm-like protein 2; Kirrel2; MGC15718; NEPH3; NEPH3Nephrin-like protein 3; nephrin-like 3; nephrin-like gene 1; NLG1; NLG1kin of irregular chiasm-like 2

Molecular Weight

Mass (kDA):
75.092 kDA

Genomic Context


Human

Location:	19q13.12
Sequence:	19; NC_000019.10 (35851635..35867146)

Tissue Specificity

Highly expressed in beta-cells of the pancreatic islets.

Subcellular Localizations

Cell membrane; Single-pass type I membrane protein. Localized along the sites of the cell contacts. Colocalizes with E-Cadherin and beta-catenin.

Diseases

Tissue Adhesions
Proteinuria Of Undiagnosed Cause
Kidney Diseases
Autoimmunity
Congenital Nephrotic Syndrome
Nephrotic Syndrome
Muscular Fasciculation
Nerve Degeneration
Focal Glomerulosclerosis
Olfactory Nerve Injuries
Diabetes Mellitus
Nephroblastoma

Injury To Kidney
Segmental Glomerulosclerosis
Retinoblastoma
Nervousness
Diabetes Mellitus, Insulin-dependent
Glomerulosclerosis (disorder)

Interacting Proteins

FHL3
PSMA3

Pathways

Cell Adhesion
Glomerular Filtration
Localization
Axon Guidance
Glycosylation
Innervation
Pathogenesis
Pancreas Development
Dna Methylation
Axonal Fasciculation

Methylation
Reverse Transcription
Organ Development
Cell Death
Slit Diaphragm Assembly

PTMs

Demethylation
Phosphorylation

Glycosylation
Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/KIRREL2

References

PMID: 12837264 by Sun C., et al. Kirrel2, a novel immunoglobulin superfamily gene expressed primarily in beta cells of the pancreatic islets.

PMID: 21697133 by Oshikawa M., et al. Full-length transcriptome analysis of human retina-derived cell lines ARPE-19 and Y79 using the vector-capping method.