Anti-Kin of IRRE-like protein 2 KIRREL2 Antibody

Product Name

Anti-Kin of IRRE-like protein 2 KIRREL2 Antibody

View all KIRREL2 Antibodies

SKU/Catalog Number

A07812

Size

0.1 mg

Form

Liquid

Description

Boster Bio Anti-Kin of IRRE-like protein 2 KIRREL2 Antibody (Catalog # A07812). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

KIRREL2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Cite This Product

Anti-Kin of IRRE-like protein 2 KIRREL2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A07812)

Host

Rabbit

Contents

KIRREL2 antibody is supplied in PBS containing 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Immunogen

KIRREL2 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human KIRREL2. The immunogen is located within amino acids 550 - 600 of KIRREL2.

Cross-reactivity

KIRREL2 antibody is human, mouse and rat reactive. At least five isoforms are are known to exist. This antibody is predicted to not cross-react with other members of the KIRREL protein family.

Reactive Species

A07812 is reactive to KIRREL2 in Human, Mouse, Rat

Observed Molecular Weight

68 kDa

Calculated molecular weight

75.1 kDa

Background of KIRREL2

KIRREL2, also known as nephrin-like 3, is a type I transmembrane protein belonging to the immunoglobulin superfamily of cell adhesion molecules (1). KIRREL2 consists of five extracellular Ig-like repeats, a transmembrane domain, several glycosylation sites and a cytoplasmic domain that has a stretch of nine conserved residues (1,2). KIRREL2 has been found to be expressed in beta cells of pancreatic islets and is involved in the regulation of both glomerular and neural development (3,4). Downregulation of KIRREL2 is implicated in several proteinuric diseases (4,5).

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

A07812 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

KIRREL2 antibody can be used for detection of KIRREL2 by Western blot at 1 - 2 μg/ml. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.

Validation Images & Assay Conditions

See full target information KIRREL2

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