Krueppel-like factor 17 Antibodies

AND Klf17 ELISA kits, Krueppel-like factor 17 Proteins

Many biological assays use antibodies to detect Krueppel-like factor 17, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Krueppel-like factor 17 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Krueppel-like factor 17 antibodies...

We validate the specificity of these antibodies to Krueppel-like factor 17 by testing them on tissues known to express Klf17 positively and negatively. Browse below to find the Klf17 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing an IHC experiment for Krueppel-like factor 17? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the KLF17 IHC Guide

Klf17 Infographic by Boster Bio

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Anti-Krueppel-like factor 17 KLF17 Antibody

Western blot analysis of KLF17 in rat liver tissue lysate with KLF17 antibody at 1 μg/ml in (A) the absence and (B) the presence of blocking peptide

Immunohistochemistry of KLF17 in mouse liver tissue with KLG17 antibody at 5 μg/ml

Human, Mouse, Rat

ELISA, IHC-P, WB

$481
Cat # A09147
0.1 mg

KLF17 (NM_173484) Human Over-expression Lysate

Human

$628
Cat # LS128209
20 µg, 100 µg

Klf17 Overview

Facts about Krueppel-like factor 17.

Krueppel-like factor 17 (Klf17)

Transcription repressor that binds to the promoter of target genes and prevents their saying. Acts as a negative regulator of epithelial-mesenchymal transition and metastasis in breast cancer.

Specifically binds the 5'-CACCC-3' sequence in the promoter of ID1, a key metastasis regulator in breast cancer, and repress its own expression. Might be a germ cell-specific transcription factor that plays important roles in spermatid differentiation and oocyte development.

Gene Information

Mouse
Gene Name:	Klf17
Uniprot:	Q8CFA7
Entrez:	75753

Family

Belongs to:

Sp1 C2H2-type zinc-finger protein family

Alternative Names

FLJ40160; KLF17; Kruppel-like factor 17; Zfp393; Zinc finger protein 393Krueppel-like factor 17; ZNF393; ZNF393novel zinc-finger protein

Molecular Weight

Mass (kDA):
38.076 kDA

Genomic Context


Mouse

Location:	4 D2.1\|4 53.46 cM
Sequence:	4;

Tissue Specificity

Exclusively expressed in testis and ovary. Localized to step 3-8 spermatids in testis and growing oocytes in ovary.

Diseases

Neoplasm Metastasis
Neoplasms
Malignant Neoplasms
Malignant Neoplasm Of Breast
Cell Invasion
Adenocarcinoma
Lung Neoplasms
Metastatic Malignant Neoplasm To The Lymph Node

Mammary Neoplasms
Adenocarcinoma Of Lung (disorder)

Pathways

Cell Growth
Rna Interference

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Klf17

References

PMID: 12351194 by Yan W., et al. Identification of Zfp393, a germ cell-specific gene encoding a novel zinc finger protein.

PMID: 19801974 by Gumireddy K., et al. KLF17 is a negative regulator of epithelial-mesenchymal transition and metastasis in breast cancer.