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- Table of Contents
Designing a Western blot for KRT18? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the KRT18 Western Blot Guide15 Citations
Facts about Keratin, type I cytoskeletal 18.
Involved in the delivery of mutated CFTR to the plasma membrane. Together with KRT8, is involved in interleukin-6 (IL-6)-mediated barrier protection.
| Human | |
|---|---|
| Gene Name: | KRT18 |
| Uniprot: | P05783 |
| Entrez: | 3875 |

| Belongs to: |
|---|
| intermediate filament family |

Cell proliferation-inducing gene 46 protein; cell proliferation-inducing protein 46; CK-18; CYK18; Cytokeratin 18; cytokeratin-18; K18; Keratin 18; keratin, type I cytoskeletal 18; keratin-18; KRT18
Mass (kDA):
48.058 kDA

| Human | |
|---|---|
| Location: | 12q13.13 |
| Sequence: | 12; NC_000012.12 (52948871..52952906) |
Expressed in colon, placenta, liver and very weakly in exocervix. Increased expression observed in lymph nodes of breast carcinoma.
Cytoplasm, perinuclear region. Nucleus, nucleolus.






PMID: 2434380 by Oshima R.G., et al. Comparison of mouse and human keratin 18: a component of intermediate filaments expressed prior to implantation.
PMID: 2454392 by Kulesh D.A., et al. Cloning of the human keratin 18 gene and its expression in nonepithelial mouse cells.
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