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- Table of Contents
Kynureninase Antibodies
AND KYNU ELISA kits, Kynureninase Proteins
Many biological assays use antibodies to detect Kynureninase, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Kynureninase in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Kynureninase antibodies...
Designing an IHC experiment for Kynureninase? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the KYNU IHC GuideKYNU Infographic by Boster Bio
All KYNU Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A06885-1
100 μg/vial
Cat # A06885-1
100 μg/vial
Human
$960
Cat # LS008942
20 µg, 100 µg
Cat # LS008942
20 µg, 100 µg
Human
$960
Cat # LS008564
20 µg, 100 µg
Cat # LS008564
20 µg, 100 µg
KYNU Overview
Facts about Kynureninase.
Kynureninase (KYNU)
Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. Has a preference for the L-3-hydroxy form.
Also has cysteine-conjugate-beta-lyase activity. .
Gene Information
| Human | |
|---|---|
| Gene Name: | KYNU |
| Uniprot: | Q16719 |
| Entrez: | 8942 |
Family
| Belongs to: |
|---|
| kynureninase family |
Alternative Names
EC 3.7.1.3; KYNU; kynureninase (L-kynurenine hydrolase); Kynureninase; L-kynurenine hydrolase
Molecular Weight
Mass (kDA):
52.352 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 2q22.2 |
| Sequence: | 2; NC_000002.12 (142877664..143055833) |
Tissue Specificity
Expressed in all tissues tested (heart, brain placenta, lung, liver, skeletal muscle, kidney and pancreas). Highest levels found in placenta, liver and lung. Expressed in all brain regions.
Subcellular Localizations
Cytoplasm, cytosol.
Diseases
- Hypertensive Disease
- Essential Hypertension
- Disease Of Adrenal Medulla
- Adult Acute Myeloblastic Leukemia
- Communicable Diseases
- Pellagra
- Leukemia, Myelocytic, Acute
- Edema
- Myeloid Leukemia
- Nervousness
- Congenital Omphalocele
Pathways
- Methylation
- Membrane Depolarization
- Phagocytosis
- Immune Response
- Tissue Homeostasis
- Excretion
PTMs
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/KYNU
bosterbio.com/bosterbio-gene-info-cards/KYNU
References
PMID: 8706755 by Alberati-Giani D., et al. Isolation and expression of a cDNA clone encoding human kynureninase.
PMID: 9180257 by Toma S., et al. Cloning and recombinant expression of rat and human kynureninase.