Laminin subunit gamma-2 Antibodies

AND LAMC2 ELISA kits, Laminin subunit gamma-2 Proteins

Many biological assays use antibodies to detect Laminin subunit gamma-2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Laminin subunit gamma-2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Laminin subunit gamma-2 antibodies...

We validate the specificity of these antibodies to Laminin subunit gamma-2 by testing them on tissues known to express LAMC2 positively and negatively. Browse below to find the LAMC2 antibody that suites your experiment. We have 6 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing a Western blot for Laminin subunit gamma-2? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.

Open the LAMC2 Western Blot Guide

LAMC2 Infographic by Boster Bio

All LAMC2 Products

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Anti-Laminin/Lamc1/Lamc2/Lamc3 Antibody Picoband®

34 Citations

IHC analysis of Laminin using anti-Laminin antibody (A03522)

Human, Mouse, Rat

IF, IHC, WB

$370
Cat # A03522
100 μg/vial

Anti-Laminin/Lamc1/Lamc2/Lamc3 Antibody Picoband®

2 Citations

IHC analysis of Laminin using anti-Laminin antibody (PB9142)

Western blot analysis of Laminin using anti-Laminin antibody (PB9142)

Human

IHC, IHC-F, WB

$370
Cat # PB9142
100 μg/vial

Anti-Laminin subunit gamma-2 LAMC2 Antibody Picoband®

IHC analysisof LAMC2 using anti-LAMC2 antibody (PA1582)

Western blot analysis of LAMC2 using anti-LAMC2 antibody (PA1582)

Human, Mouse, Rat

IHC, WB

$370
Cat # PA1582
100 μg/vial

Anti-LAMC2 Antibody Picoband®

Western blot analysis of LAMC2 using anti-LAMC2 antibody (A03214)

Human

ELISA, WB

$370
Cat # A03214
100 μg/vial

LAMC2 (NM_005562) Human Over-expression Lysate

LAMC2 Human Over-expression Lysates NM_005562

Human

$960
Cat # LS003918
20 µg, 100 µg

LAMC2 (NM_018891) Human Recombinant Protein

Coomassie blue staining of purified LAMC2 protein

$1249
Cat # PROTQ13753
20 µg

LAMC2 Overview

Facts about Laminin subunit gamma-2.

LAMC2 3D structure. Source: alphafold

Laminin subunit gamma-2 (LAMC2)

Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. Ladsin exerts cell- scattering activity toward a wide variety of cells, including epithelial, endothelial, and fibroblastic cells.

Gene Information

Human
Gene Name:	LAMC2
Uniprot:	Q13753
Entrez:	3918

Family

Belongs to:

No superfamily

Alternative Names

BM600; BM600-100kDa; Cell-scattering factor 140 kDa subunit; CSF 140 kDa subunit; CSF; EBR2; EBR2A; Epiligrin subunit gamma; kalinin (105kD); Kalinin subunit gamma; Kalinin/nicein/epiligrin 100 kDa subunit; kalinin-105kDa; ladsin (140kDa); Ladsin 140 kDa subunit; LAMB2Tlaminin, gamma 2 (nicein (100kD), kalinin (105kD), BM600 (100kD), Herlitzjunctional epidermolysis bullosa)); Laminin B2t chain; laminin subunit gamma-2; laminin, gamma 2; Laminin-5 subunit gamma; LAMNB2B2T; Large adhesive scatter factor 140 kDa subunit; MGC138491; MGC141938; nicein (100kDa); Nicein subunit gamma; nicein-100kDa

Molecular Weight

Mass (kDA):
130.976 kDA

Genomic Context


Human

Location:	1q25.3
Sequence:	1; NC_000001.11 (183186264..183245127)

Tissue Specificity

The large variant is expressed only in specific epithelial cells of embryonic and neonatal tissues. In 17-week old embryo the small variant is found in cerebral cortex, lung, and distal tubes of kidney, but not in epithelia except for distal tubuli.

Subcellular Localizations

Secreted, extracellular space, extracellular matrix, basement membrane. Major component.

Diseases

Neoplasms
Carcinoma
Malignant Neoplasms
Epidermolysis Bullosa
Cell Invasion
Junctional Epidermolysis Bullosa
Malignant Squamous Cell Neoplasm
Neoplasm Invasiveness
Bulla
Tissue Adhesions
Neoplasm Metastasis
Adenocarcinoma

Malignant Paraganglionic Neoplasm
Colorectal Neoplasms
Colorectal Cancer
Tumor Progression
Mouth Neoplasms
Dysplasia
Dermatologic Disorders

Pathways

Cell Migration
Cell Adhesion
Secretion
Methylation
Localization
Cell Motility
Pathogenesis
Wound Healing
Epithelial Cell Migration
Cell Proliferation
Cell Growth
Oncogenesis
Transport

Invasive Growth
Cell Death
Cell Differentiation
Cell-cell Adhesion
Dna Methylation
Mismatch Repair
Regeneration

PTMs

Cleavage
Methylation

Phosphorylation
Demethylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/LAMC2

References

PMID: 1383240 by Kallunki P., et al. A truncated laminin chain homologous to the B2 chain: structure, spatial expression, and chromosomal assignment.

PMID: 8306988 by Vailly J., et al. The 100-kDa chain of nicein/kalinin is a laminin B2 chain variant.

39 Publications of Boster Laminin subunit gamma-2 Antibodies & ELISA Kits

PubMed ID: PMID:25197353, Effects of transforming growth factor-β2 on myocilin expression and secretion i...
PubMed ID: 10.3892/mmr.2017.8284, The role of ursodeoxycholic acid on cholestatic hepatic fibrosis in infant rats
PubMed ID: 10.3748/wjg.v16.i6.749, Effects of in vitro cultivated Calculus Bovis compound on pulmonary lesions in r...
PubMed ID: 10.3727/096368912X655037, Electroacupuncture Promotes the Differentiation of Transplanted Bone Marrow Mese...
PubMed ID: 10.3727/096368910X528102, Bone Marrow Mesenchymal Stem Cells and Electroacupuncture Downregulate the Inhib...
PubMed ID: 10.3233/BME-151541, Observation of vascularization and protein after implanting porous silk fibroin ...
PubMed ID: 10.1111/j.1872-034X.2007.00029.x, Effect of Chinese traditional compound, Gan‐fu‐kang, on CCl4‐induced liver...
PubMed ID: 10.1021/acs.molpharmaceut.1c00121, miR-194-Loaded Gelatin Nanospheres Target MEF2C to Suppress Muscle Atrophy in a ...
PubMed ID: 10.1016/j.jss.2016.01.035, Apoptosis and death receptor signaling in diaphragm of burnt rats
PubMed ID: 10.1016/j.brainres.2010.08.072, Implantation of adult bone marrow-derived mesenchymal stem cells transfected wit...
PubMed ID: 10.1016/j.apsusc.2010.01.042, Biocompatibility of pure titanium modified by human endothelial cell-derived ext...
PubMed ID: 10.1007/s11095-013-1209-y, Electrosprayed Microparticles with Loaded pDNA-Calcium Phosphate Nanoparticles t...
PubMed ID: 10.1007/s10495-008-0277-7, Effect of burn injury on apoptosis and expression of apoptosis-related genes/pro...
PubMed ID: 10.1007/s00380-016-0834-x, Decellularized ovine arteries as biomatrix scaffold support endothelial of mesen...
PubMed ID: 10.1002/mrd.22933, Oxidized low‐density lipoprotein suppresses mouse granulosa cell differentiati...
PubMed ID: 10.1002/jbm.a.35720, Autocrine fibronectin from differentiating mesenchymal stem cells induces the ne...
PubMed ID: , Enhancement of endothelial differentiation of adipose derived mesenchymal stem c...
PubMed ID: , Graft of the NT-3 persistent delivery gelatin sponge scaffold promotes axon rege...
PubMed ID: , Perineurium-like sheath derived from long-term surviving mesenchymal stem cells ...
PubMed ID: , Cograft of neural stem cells and schwann cells overexpressing TrkC and neurotrop...
PubMed ID: , Nanoplatform Assembled from a CD44-Targeted Prodrug and Smart Liposomes for Dual...

*Showing only the more recent 20. More publications can be found for each product on its corresponding product page