LASP1 Antibodies

AND LASP1 ELISA kits, LASP1 Proteins

Many biological assays use antibodies to detect LASP1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with LASP1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop LASP1 antibodies...

We validate the specificity of these antibodies to LASP1 by testing them on tissues known to express LASP1 positively and negatively. Browse below to find the LASP1 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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LASP1 Infographic by Boster Bio

All LASP1 Products

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Specificity

Applications

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Anti-LIM and SH3 domain protein 1 LASP1 Antibody Picoband®

Anti-LASP1 antibody, PA1791, Western blottingLane 1: Rat Liver Tissue Lysate Lane 2: Rat Spleen Tissue Lysate Lane 3: Rat Intestine Tissue Lysate Lane 4: JURKAT Cell Lysate Lane 5: MCF-7 Cell Lysate Lane 6: A431 Cell Lysate Lane 7: HELA Cell Lysate
Lane 8: 293T Cell Lysate

Anti-LASP1 antibody, PA1791, IHC(P)IHC(P): Human Lung Cancer Tissue

Anti-LASP1 antibody, PA1791, ICCICC: A549 Cell

Human, Mouse, Rat

IHC, ICC, WB

$370
Cat # PA1791
100 μg/vial

Anti-LIM and SH3 domain protein 1 LASP1 Antibody Picoband®

4 Q&As

Anti-LASP1 antibody, PA1791-1, Western blottingLane 1: HELA Cell LysateLane 2: MCF-7 Cell Lysate

Human

IHC, WB

$370
Cat # PA1791-1
100 μg/vial

LASP1 (NM_006148) Human Recombinant Protein

Coomassie blue staining of purified LASP1 protein

$1249
Cat # PROTQ14847
20 µg

LASP1 (NM_006148) Human Over-expression Lysate

Human

$628
Cat # LS003927
20 µg, 100 µg

LASP1 Overview

Facts about LIM and SH3 domain protein 1.

LASP1 3D structure. Source: alphafold

LIM and SH3 domain protein 1 (LASP1)

Plays an important role in the regulation of dynamic actin-based, cytoskeletal actions. Agonist-dependent changes in LASP1 phosphorylation can also function to modulate actin-associated ion transport activities, not just in the parietal cell but also in some other F-actin-rich secretory epithelial cell types (By similarity).

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Gene Information

Human
Gene Name:	LASP1
Uniprot:	Q14847
Entrez:	3927

Family

Belongs to:

No superfamily

Alternative Names

LASP-1; LIM and SH3 domain protein 1; LIM and SH3 protein 1; Metastatic lymph node gene 50 protein; MLN 50; MLN50Lasp-1

Molecular Weight

Mass (kDA):
29.717 kDA

Genomic Context


Human

Location:	17q12
Sequence:	17; NC_000017.11 (38869859..38921770)

Subcellular Localizations

Cytoplasm, cell cortex. Cytoplasm, cytoskeleton. Associated with the F-actin rich cortical cytoskeleton.

Diseases

Malignant Neoplasms
Neoplasms
Tissue Adhesions
Malignant Neoplasm Of Breast
Mammary Neoplasms
Neoplasm Metastasis
Carcinoma
Cell Transformation, Neoplastic
Cell Invasion
Neoplasm Invasiveness
Colorectal Cancer
Colorectal Neoplasms

Liver Neoplasms
Malignant Neoplasm Of Ovary
Ovarian Neoplasm
Liver Carcinoma
Lipoma
Nervousness
Malignant Neoplasm Of Prostate

Interacting Proteins

ARID5A
CYSRT1
FXR2
GOLGA2
KRTAP4-2

LPP
LZTS2
MDFI
PSMA3
REL

RHOXF2
SH2D2A
SPRY2
TCF4
THAP1

TJP2
TRIM27
TRIP13
ZBTB9
ZC2HC1A

ZDHHC17
ZYX

Pathways

Cell Migration
Localization
Cell Motility
Cell Proliferation
Cell Growth
Cell Cycle
Wound Healing
Secretion
Pathogenesis
Rna Interference
Transport
Protein Phosphorylation
Cell Adhesion

Dna Hypermethylation
Regulation Of Signal Transduction
Platelet Activation
Mammary Gland Development
Chondrocyte Differentiation
Podosome Assembly
Cell Division

PTMs

Phosphorylation

Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/LASP1

References

PMID: 7490069 by Tomasetto C.L., et al. Identification of four novel human genes amplified and overexpressed in breast carcinoma and localized to the q11-q21.3 region of chromosome 17.

PMID: 7589475 by Tomasetto C., et al. Lasp-1 (MLN 50) defines a new LIM protein subfamily characterized by the association of LIM and SH3 domains.

1 Publications of Boster LASP1 Antibodies & ELISA Kits

PubMed ID: 32473899, Lu C,Fu L,Qian X,Dou L,Cang S.Knockdown of circular RNA circ-FARSA restricts col...

*More publications can be found for each product on its corresponding product page