Plastin-2 Antibodies

AND LCP1 ELISA kits, Plastin-2 Proteins

Many biological assays use antibodies to detect Plastin-2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Plastin-2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Plastin-2 antibodies...

We validate the specificity of these antibodies to Plastin-2 by testing them on tissues known to express LCP1 positively and negatively. Browse below to find the LCP1 antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing a Western blot for Plastin-2? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.

Open the LCP1 Western Blot Guide

Designing an IHC experiment for Plastin-2? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the LCP1 IHC Guide

LCP1 Infographic by Boster Bio

All LCP1 Products

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Product

Figures

Specificity

Applications

Price

Anti-Plastin L/LCP1 Antibody Picoband®

1 Citations

IHC analysis of LCP1 using anti-LCP1 antibody (A03361)

Human, Mouse, Rat

ELISA, Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # A03361
100 μg/vial

Anti-Plastin L Rabbit Monoclonal Antibody

Western blot analysis of Plastin L expression in Jurkat cell lysate

Human

Flow Cytometry, IP, IF, IHC, ICC, WB

$370
Cat # M03361-2
100 μl/vial

Anti-Plastin L Rabbit Monoclonal Antibody

Western blot analysis of Plastin L expression in THP1 cell lysate

Human, Mouse, Rat

IF, IHC, ICC, WB

$370
Cat # M03361-1
100 μl/vial

Plastin L (LCP1) (NM_002298) Human Over-expression Lysate

Human

$628
Cat # LS003936
20 µg, 100 µg

Anti-Zebrafish LCP1 Antibody Picoband®

Western blot analysis of LCP1 using anti-LCP1 antibody (AZQ6P698)

IHC analysis of LCP1entin/LCP1 using anti-LCP1entin/LCP1 antibody (AZQ6P698)

Zebrafish

IHC, WB

$470
Cat # AZQ6P698
100 μg/vial

LCP1 Overview

Facts about Plastin-2.

LCP1 3D structure. Source: alphafold

Plastin-2 (LCP1)

Actin-binding protein (PubMed:16636079, PubMed:17294403, PubMed:28493397). Plays a role in the activation of T-cells in response to costimulation through TCR/CD3 and CD2 or CD28 (PubMed:17294403).

Modulates the cell surface expression of IL2RA/CD25 and CD69 (PubMed:17294403). .

Gene Information

Human
Gene Name:	LCP1
Uniprot:	P13796
Entrez:	3936

Family

Belongs to:

No superfamily

Alternative Names

CP64; DKFZp781A23186; FLJ25423; FLJ26114; FLJ39956; LC64PPLS2bA139H14.1 (lymphocyte cytosolic protein 1 (L-plastin)); LCP-1; LPL; L-plastin (Lymphocyte cytosolic protein 1) (LCP-1) (LC64P); L-PLASTIN; lymphocyte cytosolic protein 1 (L-plastin); Lymphocyte cytosolic protein 1; Lymphocyte cytosolic protein-1 (plasmin); plastin 2; plastin-2

Molecular Weight

Mass (kDA):
70.288 kDA

Genomic Context


Human

Location:	13q14.13
Sequence:	13; NC_000013.11 (46125923..46182177, complement)

Tissue Specificity

Detected in intestinal microvilli, hair cell stereocilia, and fibroblast filopodia, in spleen and other lymph node-containing organs. Expressed in peripheral blood T- lymphocytes, neutrophils, monocytes, B-lymphocytes, and myeloid cells.

Subcellular Localizations

Cytoplasm, cytoskeleton. Cell junction. Cell projection. Cell projection, ruffle membrane; Peripheral membrane protein; Cytoplasmic side. Relocalizes to the immunological synapse between peripheral blood T-lymphocytes and antibody-presenting cells in response to costimulation through TCR/CD3 and CD2 or CD28 (PubMed:17294403). Associated with the actin cytoskeleton at membrane ruffles. Relocalizes to actin-rich cell projections upon serine phosphorylation (PubMed:16636079).

Diseases

Malignant Neoplasms
Neoplasms
Tissue Adhesions
Inflammation
Cell Invasion
Neoplasm Metastasis
Malignant Neoplasm Of Breast
Neoplasm Invasiveness
Malignant Neoplasm Of Lung
Infective Disorder
Retinoblastoma
Leukemia
Essential Hypertension

Swine Diseases
Malignant Tumor Of Colon
Myeloid Leukemia, Chronic
Mycobacterium Infections, Nontuberculous
Myeloid Leukemia
Cytomegalovirus Infections
Lipoid Nephrosis

Pathways

Localization
Cell Activation
Cell Motility
Macrophage Activation
Protein Phosphorylation
Cell Migration
T Cell Activation
Dosage Compensation
Cell Proliferation
Cell Development
Larval Development
Bone Resorption
Transport

Cell Adhesion
Intestinal Epithelial Cell Differentiation
Immune Response
Regulation Of Seed Development
Regulation Of Gene Expression
Chromosome Segregation
Platelet Aggregation

PTMs

Phosphorylation

Glycosylation

Cleavage

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/LCP1

References

PMID: 2252891 by Zu Y., et al. 65-kilodalton protein phosphorylated by interleukin 2 stimulation bears two putative actin-binding sites and two calcium-binding sites.

PMID: 3211125 by Lin C.-S., et al. Molecular cloning and characterization of plastin, a human leukocyte protein expressed in transformed human fibroblasts.