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LPCAT1 Antibodies
AND LPCAT1 ELISA kits, LPCAT1 Proteins
Many biological assays use antibodies to detect LPCAT1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with LPCAT1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop LPCAT1 antibodies...
Designing a Western blot for LPCAT1? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the LPCAT1 Western Blot GuideLPCAT1 Infographic by Boster Bio
All LPCAT1 Products
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LPCAT1 Overview
Facts about Lysophosphatidylcholine acyltransferase 1.
Lysophosphatidylcholine acyltransferase 1 (LPCAT1)
Possesses both acyltransferase and acetyltransferase activities (PubMed:16864775, PubMed:21498505). Action is calcium-independent (By similarity).
Mediates the conversion of 1- acyl-sn-glycero-3-phosphocholine (LPC) to phosphatidylcholine (PC) (PubMed:21498505). Displays a definite preference for saturated fatty acyl-CoAs, and 1-myristoyl or 1-palmitoyl LPC as acyl donors and acceptors, respectively (PubMed:16704971).
Gene Information
| Human | |
|---|---|
| Gene Name: | LPCAT1 |
| Uniprot: | Q8NF37 |
| Entrez: | 79888 |
Family
| Belongs to: |
|---|
| 1-acyl-sn-glycerol-3-phosphate acyltransferase family |
Alternative Names
1-acylglycerophosphocholine O-acyltransferase; Acetyl-CoA:lyso-PAF acetyltransferase; Acetyl-CoA:lyso-platelet-activating factor acetyltransferase; acyl-CoA:lysophosphatidylcholine acyltransferase 1; acyltransferase like 2; Acyltransferase-like 2; AYTL2; EC 2.3.1.-; EC 2.3.1.23,1-alkylglycerophosphocholine O-acetyltransferase; EC 2.3.1.67; FLJ12443; FLJ41609; LPC acyltransferase 1; lpcat; LPCAT-1; Lyso-PAF acetyltransferase; lysoPAFAT; LysoPC acyltransferase 1; lysophosphatidylcholine acyltransferase 1; PFAAP3; Phosphonoformate immuno-associated protein 3; regulated by phosphonoformate
Molecular Weight
Mass (kDA):
59.151 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 5p15.33 |
| Sequence: | 5; NC_000005.10 (1461427..1523960, complement) |
Subcellular Localizations
Endoplasmic reticulum membrane; Single-pass type II membrane protein. Golgi apparatus membrane; Single-pass type II membrane protein. Lipid droplet. May adopt a monotopic topology when embedded in the lipid monolayer of the lipid droplet, with both termini exposed to the cytoplasm.
Diseases
- Inflammation
- Sclerosis
- Malignant Neoplasms
- Neoplasms
- Retinal Diseases
- Respiratory Distress Syndrome, Newborn
- Respiratory Distress
- Multiple Sclerosis
- Pneumonia
- Retinal Dystrophies
- Amaurosis
Pathways
- Localization
- Reverse Transcription
- Transport
- Response To Stress
- Lung Development
- Defense Response
- Seed Development
- Lipid Homeostasis
- Cell Redox Homeostasis
PTMs
- Phosphorylation
- Oxidation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/LPCAT1
bosterbio.com/bosterbio-gene-info-cards/LPCAT1
References
PMID: 16704971 by Nakanishi H., et al. Cloning and characterization of mouse lung-type acyl- CoA:lysophosphatidylcholine acyltransferase 1 (LPCAT1): expression in alveolar type II cells and possible involvement in surfactant production.
PMID: 12693554 by Jikuya H., et al. Characterization of long cDNA clones from human adult spleen. II. The complete sequences of 81 cDNA clones.