LRFN2 Antibodies

AND LRFN2 ELISA kits, LRFN2 Proteins

Many biological assays use antibodies to detect LRFN2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with LRFN2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop LRFN2 antibodies...

We validate the specificity of these antibodies to LRFN2 by testing them on tissues known to express LRFN2 positively and negatively. Browse below to find the LRFN2 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing an IHC experiment for LRFN2? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the LRFN2 IHC Guide

LRFN2 Infographic by Boster Bio

All LRFN2 Products

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Anti-LRFN2 Antibody

Western blot analysis of LRFN2 in rat brain lysate with LRFN2 antibody at (A) 1 and (B) 2 μg/mL

Immunohistochemistry of LRFN2 in mouse brain tissue with LRFN2 antibody at 2

Immunofluorescence of LRFN2 in mouse brain tissue with LRFN2 antibody at 20 μg/mL

Human, Mouse, Rat

ELISA, IF, IHC-P, WB

$481
Cat # A11623
0.1 mg

LRFN2 Overview

Facts about Leucine-rich repeat and fibronectin type-III domain-containing protein 2.

LRFN2 3D structure. Source: alphafold

Leucine-rich repeat and fibronectin type-III domain-containing protein 2 (LRFN2)

Promotes neurite outgrowth in hippocampal neurons. Enhances the cell surface expression of 2 NMDA receptor subunits GRIN1 and GRIN2A.

May play a role in redistributing DLG4 into the cell periphery (By similarity). .

Gene Information

Human
Gene Name:	LRFN2
Uniprot:	Q9ULH4
Entrez:	57497

Family

Belongs to:

LRFN family

Alternative Names

fibronectin type III, immunoglobulin and leucine rich repeat domains 2; FIGLER2; KIAA1246; leucine rich repeat and fibronectin type III domain containing 2; LRFN2; SALM1

Molecular Weight

Mass (kDA):
84.731 kDA

Genomic Context


Human

Location:	6p21.2-p21.1
Sequence:	6; NC_000006.12 (40391589..40587364, complement)

Subcellular Localizations

Membrane; Single-pass type I membrane protein. Cell junction, synapse. Cell junction, synapse, postsynaptic cell membrane.

Diseases

Acute Erythroblastic Leukemia
Diabetes Mellitus, Non-insulin-dependent
Malignant Neoplasms
Nervousness
Liver Carcinoma
Hepatitis
Hepatitis B
Malignant Neoplasm Of Liver
Tissue Adhesions

Diabetes Mellitus
Carcinoma
Erythroblastosis

Pathways

Cellular Response To Dsrna
T Cell Differentiation
Erbb Signaling Pathway
Insulin Secretion
Cell Differentiation
Response To Dsrna
Dsrna Fragmentation
Catabolic Process

Ncrna Catabolic Process
Secretion

PTMs

Disulfide bond

Glycoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/LRFN2

References

PMID: 16630835 by Ko J., et al. SALM synaptic cell adhesion-like molecules regulate the differentiation of excitatory synapses.