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Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis (By similarity). From the nucleus: functions as a pre-mRNA splicing factor.
|Sequence:||14; NC_000014.9 (55129252..55145430)|
A major expression is found in the colonic epithelium. It is also abundant in the activated macrophages. Expressed in fetal membranes.
Cytoplasm. Nucleus. Secreted. Secreted by a non-classical secretory pathway and associates with the cell surface.
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