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- Table of Contents
MAG Antibodies
AND MAG ELISA kits, MAG Proteins
Many biological assays use antibodies to detect MAG, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with MAG in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop MAG antibodies...
Designing a Western blot for MAG? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the MAG Western Blot GuideMAG Infographic by Boster Bio
All MAG Products
Product
Figures
Specificity
Applications
Price
Anti-IMPDH2 Antibody Picoband®
1 Citations
Human, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A03021-2
100 μg/vial
Cat # A03021-2
100 μg/vial
Anti-PPP3CA Antibody Picoband®
1 Citations
Human, Rat
ELISA, Flow Cytometry, IF, ICC, WB
$370
Cat # A03026-3
100 µg/vial
Cat # A03026-3
100 µg/vial
Human, Mouse, Rat
Flow Cytometry, IF, IHC, WB
$370
Cat # M03019
100 μg/vial
Cat # M03019
100 μg/vial
Mouse, Rat
IHC, WB
$370
Cat # PA1751
100 μg/vial
Cat # PA1751
100 μg/vial
Human, Mouse, Rat
ELISA, IF, IHC-P, WB
$481
Cat # A07175
0.1 mg
Cat # A07175
0.1 mg
Human, Mouse, Rat
Flow Cytometry, IP, WB
$370
Cat # M03019-1
100 μl/vial
Cat # M03019-1
100 μl/vial
Human, Mouse, Rat
Flow Cytometry, IF, ICC, WB
$370
Cat # M03570-1
100 μl/vial
Cat # M03570-1
100 μl/vial
Human
IF, IHC, WB
$523
Cat # M07175
100 µl
Cat # M07175
100 µl
Human
Flow Cytometry, IHC, WB
$523
Cat # M07175-1
100 µl
Cat # M07175-1
100 µl
Human, Rat
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M03019-2
100 μg
Cat # M03019-2
100 μg
Human
IHC, WB
$523
Cat # M07965
100 µl
Cat # M07965
100 µl
Human, Mouse
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M03212-1
100 μg
Cat # M03212-1
100 μg
Human
ELISA
$480
Cat # EKC1342
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1342
1 kit, containing one 96-well plate and all necessary reagents
MAG Overview
Facts about Myelin-associated glycoprotein.
Myelin-associated glycoprotein (MAG)
Adhesion molecule which mediates interactions between myelinating cells and neurons by binding to neuronal sialic acid- containing gangliosides and to the glycoproteins RTN4R and RTN4RL2 (By similarity). Not required for first myelination, but seems to play a role in the maintenance of normal axon myelination.
Protects motoneurons against apoptosis, also after trauma; protection against apoptosis is likely mediated via interaction with neuronal RTN4R and RTN4RL2. Required to prevent degeneration of myelinated axons in adults; this probably depends on binding to gangliosides on the axon cell membrane (By similarity).
Gene Information
| Human | |
|---|---|
| Gene Name: | MAG |
| Uniprot: | P20916 |
| Entrez: | 4099 |
Family
| Belongs to: |
|---|
| immunoglobulin superfamily |
Alternative Names
GMAsialic acid binding Ig-like lectin 4A; MAG; myelin associated glycoprotein; myelin-associated glycoprotein; sialic acid-binding immunoglobulin-like lectin 4A; Siglec4a; Siglec-4a; S-MAG
Molecular Weight
Mass (kDA):
69.069 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 19q13.12 |
| Sequence: | 19; NC_000019.10 (35292086..35313807) |
Tissue Specificity
Both isoform 1 and isoform 2 are detected in myelinated structures in the central and peripheral nervous system, in periaxonal myelin and at Schmidt-Lanterman incisures (PubMed:9495552, PubMed:6200494). Detected in optic nerve, in oligodendroglia and in periaxonal myelin sheaths (PubMed:6200494). Detected in compact myelin (at protein level) (PubMed:6200494). Both isoform 1 and isoform 2 are detected in the central and peripheral nervous system (PubMed:9495552).
Subcellular Localizations
Cell membrane; Single-pass type I membrane protein. Membrane raft.
Diseases
- Nervousness
- Tissue Adhesions
- Polyneuropathy
- Peripheral Neuropathy
- Paraproteinemias
- Demyelinating Diseases
- Demyelination
- Autoimmune Reaction
- Monoclonal Gammapathies
- Sclerosis
- Multiple Sclerosis
- Neoplasms
Pathways
- Regeneration
- Myelination
- Cell Adhesion
- Pathogenesis
- Axon Regeneration
- Localization
- Transport
- Glycosylation
- Secretion
- Oligodendrocyte Differentiation
- Immune Response
- Translation
- Cell Death
PTMs
- Phosphorylation
- Glycosylation
- Cleavage
- Deglycosylation
- Sulphation
- Dephosphorylation
- Acylation
- Oxidation
- Methylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MAG
bosterbio.com/bosterbio-gene-info-cards/MAG
References
PMID: 2476987 by Sato S., et al. cDNA cloning and amino acid sequence for human myelin-associated glycoprotein.
PMID: 2479762 by Spagnol G., et al. Molecular cloning of human myelin-associated glycoprotein.
4 Publications of Boster MAG Antibodies & ELISA Kits
- PubMed ID: 10.1016/j.cryobiol.2021.12.002, Transplantation of rat frozen-thawed testicular tissues: Does fragment size matt...
- PubMed ID: 28408633, Heterogeneity of Cortical Lesion Susceptibility Mapping in Multiple Sclerosis
- PubMed ID: 30233061, Inhibition of neurite outgrowth using commercial myelin associated glycoprotein-...
- PubMed ID: 24687377, Yang F, Zhou X, Miao X, Zhang T, Hang X, Tie R, Liu N, Tian F, Wang F, Yuan J. B...
*More publications can be found for each product on its corresponding product page