Mastermind-like protein 3 Antibodies

AND MAML3 ELISA kits, Mastermind-like protein 3 Proteins

Many biological assays use antibodies to detect Mastermind-like protein 3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Mastermind-like protein 3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Mastermind-like protein 3 antibodies...

We validate the specificity of these antibodies to Mastermind-like protein 3 by testing them on tissues known to express MAML3 positively and negatively. Browse below to find the MAML3 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing an IHC experiment for Mastermind-like protein 3? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the MAML3 IHC Guide

MAML3 Infographic by Boster Bio

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Anti-MAML3 Antibody Picoband®

Western blot analysis of MAML3 using anti-MAML3 antibody (A07975-1)

IHC analysis of MAML3 using anti-MAML3 antibody (A07975-1)

Human

ELISA, Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # A07975-1
100 μg/vial

MAML3 Overview

Facts about Mastermind-like protein 3.

MAML3 3D structure. Source: alphafold

Mastermind-like protein 3 (MAML3)

Acts as a transcriptional coactivator for NOTCH proteins. Has been shown to amplify NOTCH-induced transcription of HES1.

Gene Information

Human
Gene Name:	MAML3
Uniprot:	Q96JK9
Entrez:	55534

Family

Belongs to:

mastermind family

Alternative Names

CAG/CTG 3; ERDA3; MAM-2; mam-3; mastermind-like 3 (Drosophila); mastermind-like protein 3; polyglutamine rich; trinucleotide repeat containing 3

Molecular Weight

Mass (kDA):
122.293 kDA

Genomic Context


Human

Location:	4q31.1
Sequence:	4; NC_000004.12 (139716753..140154184, complement)

Subcellular Localizations

Nucleus speckle. Nuclear, in a punctate manner.

Diseases

Neoplasms
Adenocarcinoma
Neoplasm Metastasis
Malignant Neoplasms
Tumor Progression
Malignant Neoplasm Of Breast
Pancreatic Adenocarcinoma
Malignant Paraganglionic Neoplasm

Chimera Disorder
Malignant Neoplasm Of Pancreas

Pathways

Drug Resistance
Stem Cell Differentiation
Cell Development
Cell Differentiation
Somitogenesis
Spinal Cord Development
Segmentation

Tissue Homeostasis

PTMs

Sumoylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MAML3

References

PMID: 12386158 by Lin S.-E., et al. Identification of new human mastermind proteins defines a family that consists of positive regulators for Notch signaling.

PMID: 12370315 by Wu L., et al. Identification of a family of mastermind-like transcriptional coactivators for mammalian notch receptors.