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- Table of Contents
MAPK14 Antibodies
AND MAPK14 ELISA kits, MAPK14 Proteins
Many biological assays use antibodies to detect MAPK14, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with MAPK14 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop MAPK14 antibodies...
Designing a Western blot for MAPK14? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the MAPK14 Western Blot GuideMAPK14 Infographic by Boster Bio
All MAPK14 Products
Product
Figures
Specificity
Applications
Price
Anti-p38 alpha/MAPK14 Antibody Picoband®
28 Citations
Human, Mouse, Rat
Flow Cytometry, IP, IF, IHC, ICC, WB
$370
Cat # A00176-2
100 μg/vial
Cat # A00176-2
100 μg/vial
Human, Mouse, Rat
IF, IHC, ICC, WB
$370
Cat # M00176-1
100 μl
Cat # M00176-1
100 μl
Anti-p38 MAPK14 Rabbit Monoclonal Antibody
1 Citations
Human, Mouse, Rat
Flow Cytometry, IP, IF, ICC, WB
$370
Cat # M00176
100 μl
Cat # M00176
100 μl
Guinea pig, Human, Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, WB
$380
Cat # A00176T180Y182
100ul
Cat # A00176T180Y182
100ul
Human, Mouse, Rat
ELISA, IP, IF, WB
$146
Cat # M00176-4
20μL, 40μL, 100μL, 200μL
Cat # M00176-4
20μL, 40μL, 100μL, 200μL
Human, Mouse, Rat
ELISA
$540
Cat # EKC2485
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2485
1 kit, containing two 96-well plates and all necessary reagents
Human, Mouse, Rat
ELISA
$540
Cat # EKC2484
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2484
1 kit, containing two 96-well plates and all necessary reagents
Human, Mouse, Rat
ELISA
$540
Cat # EKC2198
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2198
1 kit, containing two 96-well plates and all necessary reagents
Human, Mouse, Rat
ELISA
$480
Cat # EKC1422
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1422
1 kit, containing one 96-well plate and all necessary reagents
Human, Mouse, Rat
ELISA
$540
Cat # EKC2199
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2199
1 kit, containing two 96-well plates and all necessary reagents
Human, Mouse, Rat
IF, IHC, ICC, WB
$370
Cat # P00176-2
100 μl/vial
Cat # P00176-2
100 μl/vial
MAPK14 Overview
Facts about Mitogen-activated protein kinase 14.
Mitogen-activated protein kinase 14 (MAPK14)
Serine/threonine kinase which functions as an essential component of the MAP kinase signal transduction pathway. MAPK14 is one of the four p38 MAPKs which play an significant role in the cascades of cellular responses evoked by extracellular stimuli such as proinflammatory cytokines or physical strain leading to direct activation of transcription factors.
Accordingly, p38 MAPKs phosphorylate a wide assortment of proteins and it has been estimated that they might have approximately 200 to 300 substrates each. A few of the targets are downstream kinases that are activated through phosphorylation and additional phosphorylate additional targets.
Gene Information
| Human | |
|---|---|
| Gene Name: | MAPK14 |
| Uniprot: | Q16539 |
| Entrez: | 1432 |
Family
| Belongs to: |
|---|
| protein kinase superfamily |
Alternative Names
MAPK14; p38 alpha; SAPK2a
Molecular Weight
Mass (kDA):
41.293 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 6p21.31 |
| Sequence: | 6; NC_000006.12 (36027677..36122964) |
Tissue Specificity
Brain, heart, placenta, pancreas and skeletal muscle. Expressed to a lesser extent in lung, liver and kidney.
Subcellular Localizations
Cytoplasm. Nucleus.
Diseases
- Malignant Neoplasms
- Neoplasms
- Inflammation
- Inflammatory Response
- Carcinoma
- Colorectal Cancer
- Rectal Carcinoma
- Mammary Neoplasms
- Cell Transformation, Neoplastic
- Glioblastoma
- Myeloproliferative Disease
- Cholangiocarcinoma
Interacting Proteins
- AKT1
- DUSP1
- DUSP9
- MAP2K3
- MAPK1
- MAPK3
- MAPKAPK2
- MAPKAPK3
- MKNK1
- MKNK2
Pathways
- Cell Proliferation
- Cell Cycle
- Cell Death
- Secretion
- Inflammatory Response
- Cell Migration
- Cell Differentiation
- Immune Response
- Rna Interference
- Embryo Development
- Oocyte Maturation
- Regeneration
- Transport
PTMs
- Phosphorylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MAPK14
bosterbio.com/bosterbio-gene-info-cards/MAPK14
References
PMID: 7997261 by Lee J.C., et al. A protein kinase involved in the regulation of inflammatory cytokine biosynthesis.
PMID: 7696354 by Han J., et al. Molecular cloning of human p38 MAP kinase.
11 Publications of Boster MAPK14 Antibodies & ELISA Kits
- PubMed ID: 10.3892/or.2017.5861, Pseudolaric acid B inhibits neuroglioma cell proliferation through DNA damage re...
- PubMed ID: 10.3892/mmr.2019.10785, Placental growth factor gene silencing mitigates the epithelial‑to‑mesenchym...
- PubMed ID: 10.1016/j.jep.2017.03.012, The vascular protective effects of Anoectochilus roxburghii polysaccharose under...
- PubMed ID: 10.1016/j.ijbiomac.2017.05.191, β-d-glucan from Antrodia Camphorata ameliorates LPS-induced inflammation and RO...
- PubMed ID: 10.1007/s12031-017-0994-x, Let-7d microRNA Attenuates 6-OHDA-Induced Injury by Targeting Caspase-3 in MN9D ...
- PubMed ID: 31611791, Wei X,Zhu Q,Liu N,Xu L,Wei S,Fan Z,Sun C,Zhao Y,Qiao M,Wu J,Hu D,Wang Y,Sun P.Ne...
- PubMed ID: 32794226, Ma G,Kimatu BM,Yang W,Pei F,Zhao L,Du H,Su A,Hu Q,Xiao H.Preparation of newly id...
- PubMed ID: 31611791, Neuroprotective Effects and Mechanisms of Zhenlong Xingnao Capsule in In Vivo an...
- PubMed ID: 25206865, Vasopressin decreases neuronal apoptosis during cardiopulmonary resuscitation
- PubMed ID: 29048616, Liao S, Xiao S, Chen H, Zhang M, Chen Z, Long Y, Gao L, He J, Ge Y, Yi W, Wu M, ...
- PubMed ID: 24700345, Zhao B, Li X. Oncol Rep. 2014 Jun;31(6):2769-75. Doi: 10.3892/Or.2014.3126. Epub...
*More publications can be found for each product on its corresponding product page