This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
Thrombopoietin receptor Antibodies
AND MPL ELISA kits, Thrombopoietin receptor Proteins
Many biological assays use antibodies to detect Thrombopoietin receptor, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Thrombopoietin receptor in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Thrombopoietin receptor antibodies...
Designing a Western blot for Thrombopoietin receptor? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the MPL Western Blot GuideMPL Infographic by Boster Bio
All MPL Products
Product
Figures
Specificity
Applications
Price
Mouse Thrombopoietin/TPO ELISA Kit PicoKine®
2 Citations
Mouse
ELISA
$499
Cat # EK0517
96 wells/kit, with removable strips.
Cat # EK0517
96 wells/kit, with removable strips.
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A03223-2
100 µg/vial
Cat # A03223-2
100 µg/vial
Mouse, Rat
ELISA, IHC, WB
$370
Cat # A03222-1
100 μg/vial
Cat # A03222-1
100 μg/vial
Anti-DR3/Tnfrsf25 Antibody Picoband®
1 Citations
Mouse, Rat
ELISA, Flow Cytometry, WB
$370
Cat # A03227-3
100 μg/vial
Cat # A03227-3
100 μg/vial
Mouse
ELISA
$750
Cat # EK1436
96 wells/kit, with removable strips.
Cat # EK1436
96 wells/kit, with removable strips.
Human
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M00483-1
100 μg
Cat # M00483-1
100 μg
SDS-PAGE, Bioactivity
$287
Cat # PROTP40226
Starting from 10ug
Cat # PROTP40226
Starting from 10ug
Human
Cell Culture
$77
Cat # PROTP40225-6
5ug,20ug,100ug
Cat # PROTP40225-6
5ug,20ug,100ug
MPL Overview
Facts about Thrombopoietin receptor.
Thrombopoietin receptor (MPL)
Receptor for thrombopoietin that functions as a key regulator of megakaryopoiesis and platelet production. May represent a regulatory molecule specific for TPO-R-dependent immune responses.
.
Gene Information
| Human | |
|---|---|
| Gene Name: | MPL |
| Uniprot: | P40238 |
| Entrez: | 4352 |
Family
| Belongs to: |
|---|
| type I cytokine receptor family |
Alternative Names
CD110 antigen; CD110; c-Mpl; MPL; MPLV; Myeloproliferative leukemia protein; myeloproliferative leukemia virus oncogene; Proto-oncogene c-Mpl; Thrombopoietin R; thrombopoietin receptor; TpoR; TPO-R; TPORMPLV
Molecular Weight
Mass (kDA):
71.245 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 1p34.2 |
| Sequence: | 1; NC_000001.11 (43336875..43354466) |
Tissue Specificity
Expressed at a low level in a large number of cells of hematopoietic origin. Isoform 1 and isoform 2 are always found to be coexpressed.
Subcellular Localizations
Cell membrane; Single-pass type I membrane protein. Golgi apparatus. Cell surface.
Diseases
- Thrombocytosis
- Myeloproliferative Disease
- Neoplasms
- Leukemia
- Thrombocythemia, Essential
- Primary Myelofibrosis
- Polycythemia Vera
- Polycythemia
- Myeloid Leukemia
- Malignant Neoplasms
- Leukemia, Myelocytic, Acute
- Anemia
Interacting Proteins
- JAK2
Pathways
- Immune Response
- Pathogenesis
- Cell Proliferation
- Cell Growth
- Megakaryocyte Differentiation
- Localization
- Secretion
- Megakaryocyte Development
- Platelet Aggregation
- Hypersensitivity
- Platelet Activation
- Cell Cycle
- Cell Differentiation
PTMs
- Phosphorylation
- Glycosylation
- Cleavage
- Methylation
- Ubiquitination
- Biotinylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MPL
bosterbio.com/bosterbio-gene-info-cards/MPL
References
PMID: 1608974 by Vigon I., et al. Molecular cloning and characterization of MPL, the human homolog of the v-mpl oncogene: identification of a member of the hematopoietic growth factor receptor superfamily.
PMID: 8020956 by Mignotte V., et al. Structure and transcription of the human c-mpl gene (MPL).
3 Publications of Boster Thrombopoietin receptor Antibodies & ELISA Kits
- PubMed ID: 10.1096/fj.201902142R, Deficiency of platelet adhesion molecule CD226 causes megakaryocyte development ...
- PubMed ID: 10.1080/08923973.2017.1392564, Improvement of icaritin on hematopoietic function in cyclophosphamide-induced my...
- PubMed ID: 27378920, Extracted Triterpenes from Antrodia cinnamomea Reduce the Inflammation to Promot...
*More publications can be found for each product on its corresponding product page