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- Table of Contents
Mucin-5B Antibodies
AND MUC5B ELISA kits, Mucin-5B Proteins
Many biological assays use antibodies to detect Mucin-5B, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Mucin-5B in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Mucin-5B antibodies...
Designing a Western blot for Mucin-5B? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the MUC5B Western Blot GuideDesigning an IHC experiment for Mucin-5B? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the MUC5B IHC GuideMUC5B Infographic by Boster Bio
All MUC5B Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
ELISA, IP, IF, IHC, WB
$146
Cat # M00719-1
20μL, 40μL, 100μL, 200μL
Cat # M00719-1
20μL, 40μL, 100μL, 200μL
MUC5B Overview
Facts about Mucin-5B.
Mucin-5B (MUC5B)
Gel-forming mucin that's thought to contribute to the lubricating and viscoelastic properties of whole saliva and cervical mucus. .
Gene Information
| Human | |
|---|---|
| Gene Name: | MUC5B |
| Uniprot: | Q9HC84 |
| Entrez: | 727897 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
high molecular weight salivary mucin MG1; mucin 5, subtype B, tracheobronchial; mucin 5B, oligomeric mucus/gel-forming; sublingual gland mucin; tracheobronchial
Molecular Weight
Mass (kDA):
596.34 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 11p15.5 |
| Sequence: | 11; NC_000011.10 (1223066..1262172) |
Tissue Specificity
Expressed on surface airway epithelia. Expressed mainly in mucous cells of submucosal glands of airway tissues. Highly expressed in the sublingual gland. Also found in submaxillary glands, endocervix, gall bladder, and pancreas.
Subcellular Localizations
Secreted.
Diseases
- Mucinous Adenocarcinoma
- Malignant Neoplasms
- Neoplasms
- Inflammation
- Fibrosis
- Carcinoma
- Adenocarcinoma
- Asthma
- Cystic Fibrosis
- Lung Diseases
- Salivary Gland Diseases
- Metaplasia
Pathways
- Secretion
- Pathogenesis
- Glycosylation
- Localization
- Cell Differentiation
- Mucus Secretion
- Cell Proliferation
- Gallstone Formation
- Transport
- Proteolysis
- Immune Response
- Epithelial Cell Differentiation
- Sulfation
PTMs
- Glycosylation
- Phosphorylation
- Cleavage
- Deglycosylation
- Methylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MUC5B
bosterbio.com/bosterbio-gene-info-cards/MUC5B
References
PMID: 11713095 by Chen Y., et al. Characterization of human mucin 5B gene expression in airway epithelium and the genomic clone of the amino-terminal and 5'-flanking region.
PMID: 9790959 by Offner G.D., et al. The amino-terminal sequence of MUC5B contains conserved multifunctional D domains: implications for tissue-specific mucin functions.