MTMR3 Antibodies

AND MTMR3 ELISA kits, MTMR3 Proteins

Many biological assays use antibodies to detect MTMR3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with MTMR3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop MTMR3 antibodies...

We validate the specificity of these antibodies to MTMR3 by testing them on tissues known to express MTMR3 positively and negatively. Browse below to find the MTMR3 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing an IHC experiment for MTMR3? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the MTMR3 IHC Guide

MTMR3 Infographic by Boster Bio

All MTMR3 Products

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Anti-MTMR3 Antibody Picoband®

Western blot analysis of MTMR3 using anti-MTMR3 antibody (A05937-1)

IHC analysis of MTMR3 using anti-MTMR3 antibody (A05937-1)

Human

ELISA, Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # A05937-1
100 μg/vial

MTMR3 Overview

Facts about Myotubularin-related protein 3.

MTMR3 3D structure. Source: alphafold

Myotubularin-related protein 3 (MTMR3)

Phosphatase that acts on lipids with a phosphoinositol headgroup. Has phosphatase activity towards phosphatidylinositol 3-phosphate and phosphatidylinositol 3,5-bisphosphate.

May also dephosphorylate proteins phosphorylated on Ser, Thr, and Tyr residues (PubMed:10733931). .

Gene Information

Human
Gene Name:	MTMR3
Uniprot:	Q13615
Entrez:	8897

Family

Belongs to:

protein-tyrosine phosphatase family

Alternative Names

FLJ32333; FYVE-DSP1FYVE domain containing 10; myotubularin related protein 3

Molecular Weight

Mass (kDA):
133.619 kDA

Genomic Context


Human

Location:	22q12.2
Sequence:	22; NC_000022.11 (29883169..30030868)

Subcellular Localizations

Cytoplasm. Membrane; Peripheral membrane protein.

Diseases

Myopathy
Congenital Structural Myopathy
Malignant Neoplasms
Charcot-marie-tooth Disease
Malignant Neoplasm Of Stomach
Cholangiocarcinoma
Stomach Neoplasms
Mutation, Out-of-frame
Neurodegenerative Disorders
Inflammatory Bowel Diseases
Intestinal Diseases
Endoplasmic Reticulum Stress

Carcinoma
Posttransfusion Purpura
Colorectal Cancer
Low-frequency Microsatellite Instability
Hereditary Diseases
High-frequency Microsatellite Instability

Interacting Proteins

MTOR
RPTOR

Pathways

Localization
Autophagy
Protein Phosphorylation
Reverse Transcription
Cell Migration
Immune Response
Metaphase
Regulation Of Autophagy

Pathogenesis
Catabolic Process

PTMs

Dephosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MTMR3

References

PMID: 10733931 by Zhao R., et al. FYVE-DSP1, a dual-specificity protein phosphatase containing an FYVE domain.

PMID: 9736772 by Laporte J., et al. Characterization of the myotubularin dual specificity phosphatase gene family from yeast to human.