NCOA5 Antibodies

AND NCOA5 ELISA kits, NCOA5 Proteins

Many biological assays use antibodies to detect NCOA5, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with NCOA5 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop NCOA5 antibodies...

We validate the specificity of these antibodies to NCOA5 by testing them on tissues known to express NCOA5 positively and negatively. Browse below to find the NCOA5 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing an IHC experiment for NCOA5? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the NCOA5 IHC Guide

NCOA5 Infographic by Boster Bio

All NCOA5 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-NCOA5 Antibody Picoband®

Western blot analysis of NCOA5 using anti-NCOA5 antibody (A07810-2)

IHC analysis of NCOA5 using anti-NCOA5 antibody (A07810-2)

Human, Mouse, Rat

ELISA, Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # A07810-2
100 µg/vial

NCOA5 (NM_020967) Human Over-expression Lysate

Human

$960
Cat # LS057727
20 µg, 100 µg

Anti-Nuclear receptor coactivator 5 NCOA5 Antibody

Immunohistochemistry analysis of paraffin-embedded human brain tissue, using NCOA5 Antibody

Human, Mouse

ELISA, IF, IHC, ICC

$335
Cat # A07810
100ul

NCOA5 Overview

Facts about Nuclear receptor coactivator 5.

NCOA5 3D structure. Source: alphafold

Nuclear receptor coactivator 5 (NCOA5)

Nuclear receptor coregulator that could have both coactivator and corepressor functions. Interacts with nuclear receptors for steroids (ESR1 and ESR2) independently of the steroid binding domain (AF-2) of the ESR receptors, as well as with the orphan nuclear receptor NR1D2.

Involved in the coactivation of nuclear steroid receptors (ER) and the corepression of MYC in response to 17-beta-estradiol (E2). .

Gene Information

Human
Gene Name:	NCOA5
Uniprot:	Q9HCD5
Entrez:	57727

Family

Belongs to:

No superfamily

Alternative Names

CIAbA465L10.6; Coactivator independent of AF-2; KIAA1637; NCoA-5; nuclear receptor coactivator 5

Molecular Weight

Mass (kDA):
65.536 kDA

Genomic Context


Human

Location:	20q13.12
Sequence:	20; NC_000020.11 (46060991..46089962, complement)

Tissue Specificity

Widely expressed.

Subcellular Localizations

Nucleus.

Diseases

Autoimmunity
Cell Transformation, Neoplastic
Psoriasis
Endometrial Neoplasms
Endometrial Polyp
Autoimmune Diseases
Carcinoma
Arthritis
Autoimmune Reaction
Neoplasms

Endometrial Carcinoma
Chimera Disorder
Rheumatoid Arthritis
Dermatologic Disorders

Interacting Proteins

Nr1d2

Pathways

Pathogenesis

PTMs

Acetylation

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/NCOA5

References

PMID: 11113208 by Sauve F., et al. CIA, a novel estrogen receptor coactivator with a bifunctional nuclear receptor interacting determinant.

PMID: 15073177 by Jiang C., et al. TIP30 interacts with an estrogen receptor alpha-interacting coactivator CIA and regulates c-myc transcription.