This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
NDUFS2 Antibodies
AND NDUFS2 ELISA kits, NDUFS2 Proteins
Many biological assays use antibodies to detect NDUFS2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with NDUFS2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop NDUFS2 antibodies...
Designing a Western blot for NDUFS2? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the NDUFS2 Western Blot GuideDesigning an IHC experiment for NDUFS2? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the NDUFS2 IHC GuideNDUFS2 Infographic by Boster Bio
All NDUFS2 Products
Product
Figures
Specificity
Applications
Price
Anti-NDUFS2 Antibody Picoband®
1 Citations
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A05618-3
100 μg/vial
Cat # A05618-3
100 μg/vial
Human, Mouse, Rat
IP, IHC, WB
$370
Cat # M05618-1
100 μl/vial
Cat # M05618-1
100 μl/vial
NDUFS2 Overview
Facts about NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial.
NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial (NDUFS2)
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is thought to belong to the minimal assembly required for catalysis. Sophisticated I works in the transport of electrons from NADH to the respiratory chain.
The immediate electron acceptor for the enzyme is believed to be ubiquinone (PubMed:12611891). .
Gene Information
| Human | |
|---|---|
| Gene Name: | NDUFS2 |
| Uniprot: | O75306 |
| Entrez: | 4720 |
Family
| Belongs to: |
|---|
| complex I 49 kDa subunit family |
Alternative Names
CI-49; CI-49kD; complex 1, mitochondrial respiratory chain, 49-KD subunit; complex I 49kDa subunit; Complex I-49kD; EC 1.6.5.3; EC 1.6.99.3; EC 1.6.99.5; NADH dehydrogenase (ubiquinone) Fe-S protein 2 (49kD) (NADH-coenzyme Qreductase); NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Qreductase); NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial; NADH-ubiquinone oxidoreductase 49 kDa subunit; NADH-ubiquinone oxidoreductase NDUFS2 subunit
Molecular Weight
Mass (kDA):
52.546 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 1q23.3 |
| Sequence: | 1; NC_000001.11 (161197417..161214395) |
Subcellular Localizations
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Diseases
- Nicotinamide Adenine Dinucleotide Coenzyme Q Reductase Deficiency
- Leigh Disease
- Cardiomyopathies
- Parkinson Disease
- Mitochondrial Diseases
- Mitochondrial Encephalomyopathies
- Acidosis
- Nerve Degeneration
- Obesity
- Acidosis, Lactic
- Optic Atrophy
- Sclerosis
Interacting Proteins
- NDUFS3
Pathways
- Oxidative Phosphorylation
- Translation
- Transport
- Cell Proliferation
- Electron Transport
- Aging
- Proteolysis
- Neurogenesis
- Pigmentation
- Thermotaxis
- Phototaxis
PTMs
- Phosphorylation
Research Areas
- Core ESC-Like Genes
- Stem Cell Markers
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/NDUFS2
bosterbio.com/bosterbio-gene-info-cards/NDUFS2
References
PMID: 9647766 by Loeffen J., et al. cDNA sequence and chromosomal localization of the remaining three human nuclear encoded iron sulphur protein (IP) subunits of complex I: the human IP fraction is completed.
PMID: 9585441 by Procaccio V., et al. Mapping to 1q23 of the human gene (NDUFS2) encoding the 49-kDa subunit of the mitochondrial respiratory complex I and immunodetection of the mature protein in mitochondria.