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Homeobox protein Nkx-2.2 Antibodies
AND NKX2-2 ELISA kits, Homeobox protein Nkx-2.2 Proteins
Many biological assays use antibodies to detect Homeobox protein Nkx-2.2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Homeobox protein Nkx-2.2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Homeobox protein Nkx-2.2 antibodies...
Designing a Western blot for Homeobox protein Nkx-2.2? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the NKX2-2 Western Blot GuideDesigning an IHC experiment for Homeobox protein Nkx-2.2? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the NKX2-2 IHC GuideNKX2-2 Infographic by Boster Bio
All NKX2-2 Products
Product
Figures
Specificity
Applications
Price
Human
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A00738-2
100 μg/vial
Cat # A00738-2
100 μg/vial
Human, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M01322-1
100 μl
Cat # M01322-1
100 μl
Human, Mouse, Rat
ELISA, IF, IHC-P, WB
$481
Cat # A04740
0.1 mg
Cat # A04740
0.1 mg
Human, Mouse, Rat
ELISA, IF, IHC-P, WB
$481
Cat # A12535-1
0.1 mg
Cat # A12535-1
0.1 mg
Human, Mouse
ELISA, IF, ICC, WB
$481
Cat # A16202-1
0.1 mg
Cat # A16202-1
0.1 mg
Human, Mouse
ELISA, IF, IHC-P, WB
$481
Cat # A09381-1
0.1 mg
Cat # A09381-1
0.1 mg
Human, Mouse, Rat
ELISA, IF, IHC-P, WB
$481
Cat # A01322
0.1 mg
Cat # A01322
0.1 mg
NKX2-2 Overview
Facts about Homeobox protein Nkx-2.2.
Homeobox protein Nkx-2.2 (NKX2-2)
Transcriptional activator involved in the creation of insulin-producting beta cells in the endocrine pancreas (By similarity). May also be involved in specifying diencephalic neuromeric boundaries, and in controlling the expression of genes that play a role in axonal guidance.
Binds to elements within the NEUROD1 promoter (By similarity). .
Gene Information
| Human | |
|---|---|
| Gene Name: | NKX2-2 |
| Uniprot: | O95096 |
| Entrez: | 4821 |
Family
| Belongs to: |
|---|
| NK-2 homeobox family |
Alternative Names
Homeobox protein NK-2 homolog B; NK-2 (Drosophila) homolog B; NK2 homeobox 2; NK2 transcription factor related, locus 2 (Drosophila); NK2 transcription factor related, locus 2; NK2 transcription factor-like protein B; NKX2.2; NKX2.2homeobox protein Nkx-2.2; NKX2B; NKX2BNK-2 homolog B
Molecular Weight
Mass (kDA):
30.133 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 20p11.22 |
| Sequence: | 20; NC_000020.11 (21511010..21514064, complement) |
Subcellular Localizations
Nucleus.
Diseases
- Parkinson Disease
- Neoplasms
- Nervousness
- Diabetes Mellitus
- Lymphohistiocytosis, Hemophagocytic
- Mental Disorders
- Diabetes Mellitus, Non-insulin-dependent
- Neoplasm Metastasis
- Fracture Of First Cervical Vertebra
- Malignant Neoplasm Of Breast
- Glioma
- Ewings Sarcoma-primitive Neuroectodermal Tumor (pnet)
- Insulin Resistance
Pathways
- Pancreas Development
- Methylation
- Dna Methylation
- Cell Cycle
- Gliogenesis
- Developmental Process
- Cell Development
- Insulin Secretion
- Cell Fate Commitment
- Neurogenesis
- Neuron Development
- Histone Modification
PTMs
- Methylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/NKX2-2
bosterbio.com/bosterbio-gene-info-cards/NKX2-2
References
PMID: 9703340 by Furuta H., et al. Beta-cell transcription factors and diabetes: mutations in the coding region of the BETA2/NeuroD1 (NEUROD1) and Nkx2.2 (NKX2B) genes are not associated with maturity-onset diabetes of the young in Japanese.