NLRP9 Antibodies

AND NLRP9 ELISA kits, NLRP9 Proteins

Many biological assays use antibodies to detect NLRP9, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with NLRP9 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop NLRP9 antibodies...

We validate the specificity of these antibodies to NLRP9 by testing them on tissues known to express NLRP9 positively and negatively. Browse below to find the NLRP9 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing an IHC experiment for NLRP9? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the NLRP9 IHC Guide

NLRP9 Infographic by Boster Bio

All NLRP9 Products

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Product

Figures

Specificity

Applications

Price

Anti-NLRP9 Antibody Picoband®

Western blot analysis of NLRP9 using anti-NLRP9 antibody (A14119-1)

Human

ELISA, WB

$370
Cat # A14119-1
100 µg/vial

Anti-NOD6 NLRP9 Antibody

Western blot analysis of NOD6 in EL4 cell lysate with NOD6 antibody at 1 μg/mL in the (A) absence and (B) presence of blocking peptide

Immunohistochemistry of NOD6 in human testis tissue with NOD6 antibody at 10 μg/mL

Immunofluorescence of NOD6 in human testis tissue with NOD6 antibody at 20 μg/mL

Human, Mouse

ELISA, IF, IHC-P, WB

$481
Cat # A14119
0.1 mg

NLRP9 (NM_176820) Human Over-expression Lysate

Human

$960
Cat # LS338321
20 µg, 100 µg

NLRP9 Overview

Facts about NACHT, LRR and PYD domains-containing protein 9.

NACHT, LRR and PYD domains-containing protein 9 (NLRP9)

As the sensor component of the NLRP9 inflammasome, plays a crucial role in innate immunity and inflammation. In response to pathogens, including rotavirus, initiates the formation of the inflammasome polymeric complex, made of NLRP9, PYCARD and CASP1.

Recruitment of proCASP1 to the inflammasome promotes its activation and CASP1-catalyzed IL1B and IL18 maturation and release in the extracellular milieu. The active cytokines stimulate inflammatory responses.

Gene Information

Human
Gene Name:	NLRP9
Uniprot:	Q7RTR0
Entrez:	338321

Family

Belongs to:

NLRP family

Alternative Names

NACHT, LRR and PYD domains-containing protein 9

Molecular Weight

Mass (kDA):
113.312 kDA

Genomic Context


Human

Location:	19q13.42
Sequence:	19; NC_000019.10 (55708438..55738402, complement)

Tissue Specificity

Expressed in ileum intestinal epithelial cells. Not detected in peripheral blood mononuclear cells (PubMed:28636595). Expressed in cerebral endothelial cells and, at much lower levels, in brain pericytes (PubMed:28432035).

Subcellular Localizations

Cytoplasm. Inflammasome.

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/NLRP9

References

PMID: 12563287 by Tschopp J., et al. NALPs: a novel protein family involved in inflammation.

PMID: 12766759 by Inohara N., et al. NODs: intracellular proteins involved in inflammation and apoptosis.