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- Table of Contents
NRF1 Antibodies
AND NRF1 ELISA kits, NRF1 Proteins
Many biological assays use antibodies to detect NRF1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with NRF1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop NRF1 antibodies...
Designing a Western blot for NRF1? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the NRF1 Western Blot GuideDesigning an IHC experiment for NRF1? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the NRF1 IHC GuideNRF1 Infographic by Boster Bio
All NRF1 Products
Product
Figures
Specificity
Applications
Price
Anti-NRF1 Antibody Picoband®
2 Citations
Human, Mouse, Rat
ELISA, Flow Cytometry, IHC, WB
$370
Cat # A01129-2
100 μg/vial
Cat # A01129-2
100 μg/vial
Human
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M01129-1
100 μg/vial
Cat # M01129-1
100 μg/vial
Human, Mouse, Rat
IHC, ICC, WB
$370
Cat # PA1948
100 μg/vial
Cat # PA1948
100 μg/vial
Human, Mouse, Rat
Flow Cytometry, IP, IF, IHC, ICC, WB
$370
Cat # M01129
100 μl
Cat # M01129
100 μl
NRF1 Overview
Facts about Nuclear respiratory factor 1.
Nuclear respiratory factor 1 (NRF1)
Transcription factor that activates the expression of this EIF2S1 (EIF2-alpha) gene. Links the transcriptional modulation of key metabolic genes to cellular growth and development.
Implicated in the control of nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication. .
Gene Information
| Human | |
|---|---|
| Gene Name: | NRF1 |
| Uniprot: | Q16656 |
| Entrez: | 4899 |
Family
| Belongs to: |
|---|
| NRF1/Ewg family |
Alternative Names
Alpha palindromic-binding protein; ALPHA-PAL; EWG; HBZ17; LCR-F1; NFE2L1; Nrf1; NRF-1; nuclear respiratory factor 1; TCF11
Molecular Weight
Mass (kDA):
53.541 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 7q32.2 |
| Sequence: | 7; NC_000007.14 (129611720..129757082) |
Tissue Specificity
Ubiquitously expressed with strongest expression in skeletal muscle.
Subcellular Localizations
Nucleus.
Diseases
- Malignant Neoplasms
- Neoplasms
- Diabetes Mellitus
- Diabetes Mellitus, Non-insulin-dependent
- Obesity
- Insulin Resistance
- Inflammation
- Malignant Neoplasm Of Breast
- Fatty Liver
- Steatohepatitis
- Neurodegenerative Disorders
- Hypoxia
Interacting Proteins
- CCND1
- FHL2
- POGZ
- SIRT7
- SP4
- TRAF2
Pathways
- Transport
- Oxidative Phosphorylation
- Pathogenesis
- Translation
- Cell Proliferation
- Localization
- Electron Transport
- Methylation
- Cell Death
- Electron Transport Chain
- Aging
- Cell Cycle
- Fatty Acid Oxidation
PTMs
- Phosphorylation
- Oxidation
- Methylation
- Ubiquitination
- Glycosylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/NRF1
bosterbio.com/bosterbio-gene-info-cards/NRF1
References
PMID: 8253388 by Virbasius C.A., et al. NRF-1, an activator involved in nuclear-mitochondrial interactions, utilizes a new DNA-binding domain conserved in a family of developmental regulators.
PMID: 8034649 by Efiok B.J.S., et al. A key transcription factor for eukaryotic initiation factor-2 alpha is strongly homologous to developmental transcription factors and may link metabolic genes to cellular growth and development.
3 Publications of Boster NRF1 Antibodies & ELISA Kits
- PubMed ID: 10.1152/ajpgi.00270.2015, Defect of mitochondrial respiratory chain is a mechanism of ROS overproduction i...
- PubMed ID: 32158360, Nazmeen A,Chen G,Ghosh TK,Maiti S.Breast cancer pathogenesis is linked to the in...
- PubMed ID: 26585415, Defect of mitochondrial respiratory chain is a mechanism of ROS overproduction ...
*More publications can be found for each product on its corresponding product page