Nacc1 Antibodies

AND Nacc1 ELISA kits, Nacc1 Proteins

Many biological assays use antibodies to detect Nacc1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Nacc1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Nacc1 antibodies...

We validate the specificity of these antibodies to Nacc1 by testing them on tissues known to express Nacc1 positively and negatively. Browse below to find the Nacc1 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing a Western blot for Nacc1? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.

Open the NACC1 Western Blot Guide

Designing an IHC experiment for Nacc1? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the NACC1 IHC Guide

Nacc1 Infographic by Boster Bio

All Nacc1 Products

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Product

Figures

Specificity

Applications

Price

Anti-Nac1/NACC1 Antibody Picoband®

Western blot analysis of Nac1/NACC1 using anti-Nac1/NACC1 antibody (A08675-3)

IHC analysis of Nac1/NACC1 using anti-Nac1/NACC1 antibody (A08675-3)

Human

ELISA, Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # A08675-3
100 μg/vial

Nac1 (NACC1) (NM_052876) Human Over-expression Lysate

Human

$628
Cat # LS112939
20 µg, 100 µg

Nacc1 Overview

Facts about Nucleus accumbens-associated protein 1.

Nucleus accumbens-associated protein 1 (Nacc1)

Functions as a transcriptional repressor. Seems to function as a transcriptional corepressor in neuronal cells during recruitment of HDAC3 and HDAC4.

Contributes to tumor development, and tumor cell proliferation and survival. This may be mediated at least in part through repressing transcriptional activity of GADD45GIP1.

Gene Information

Mouse
Gene Name:	Nacc1
Uniprot:	Q7TSZ8
Entrez:	66830

Family

Belongs to:

No superfamily

Alternative Names

BEND8; BTB (POZ) domain containing 14B; BTB/POZ domain-containing protein 14B; BTBD14B; BTBD30; NAC1; NAC1BEN domain containing 8; NAC-1FLJ37383; NACC1; nucleus accumbens associated 1, BEN and BTB (POZ) domain containing; nucleus accumbens-associated protein 1; transcriptional repressor NAC1

Molecular Weight

Mass (kDA):
56.537 kDA

Genomic Context


Mouse

Location:	8 C2\|8 41.02 cM
Sequence:	8;

Tissue Specificity

Ubiquitously expressed with higher expression in the brain, kidney and liver, and at lower levels in heart, lung and testes.

Diseases

Malignant Neoplasms
Carcinoma
Neoplasms
Ovarian Neoplasm
Malignant Neoplasm Of Ovary
Ovarian Serous Adenocarcinoma
Neuroblastoma
Cystadenocarcinoma, Serous
Neoplasm Metastasis
Neoplasm Invasiveness
Epithelial Ovarian Cancer
Adenocarcinoma

Neoplasm Recurrence, Local
Uterine Cervical Neoplasm
Endometrial Polyp
Cell Invasion
Cell Transformation, Neoplastic
Metastatic Malignant Neoplasm To The Lymph Node
Malignant Tumor Of Cervix

Pathways

Cell Proliferation
Sensitization
Localization
Cell Growth
Cell Migration
Cell Cycle
Oncogenesis
Cytokinesis
Interphase
Drug Resistance
S Phase
Pathogenesis
T Cell Selection

Programmed Cell Death
Cellular Senescence
Proteolysis
Regulation Of Gene Expression
Regulation Of Autophagy
Stem Cell Proliferation
Response To Cocaine

PTMs

Phosphorylation

Deacetylation

Acetylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Nacc1

References

PMID: 14521994 by Mackler S.A., et al. The mouse Nac1 gene, encoding a cocaine-regulated bric-a-brac tramtrac broad complex/pox virus and zinc finger protein, is regulated by AP1.

PMID: 17130457 by Nakayama K., et al. A BTB/POZ protein, NAC-1, is related to tumor recurrence and is essential for tumor growth and survival.