PAIP1 Antibodies

AND PAIP1 ELISA kits, PAIP1 Proteins

Many biological assays use antibodies to detect PAIP1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PAIP1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PAIP1 antibodies...

We validate the specificity of these antibodies to PAIP1 by testing them on tissues known to express PAIP1 positively and negatively. Browse below to find the PAIP1 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PAIP1 Infographic by Boster Bio

All PAIP1 Products

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Product

Figures

Specificity

Applications

Price

Anti-PAIP1 Antibody

Western blot analysis of extracts of various cell lines, using PAIP1 antibody at 1:1000 dilution

Human, Mouse, Rat

$405
Cat # A07792
100ul

PAIP1 (NM_182789) Human Recombinant Protein

Coomassie blue staining of purified PAIP1 protein

$1062
Cat # PROTQ9H074
20 µg

PAIP1 (NM_182789) Human Over-expression Lysate

PAIP1 Human Over-expression Lysates NM_182789

Human

$628
Cat # LS010605
20 µg, 100 µg

Anti-PAIP1 Antibody Picoband®

Western blot analysis of PAIP1 using anti-PAIP1 antibody (A07792-2)

IHC analysis of PAIP1 using anti-PAIP1 antibody (A07792-2)

Human

ELISA, Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # A07792-2
100 µg/vial

PAIP1 Overview

Facts about Polyadenylate-binding protein-interacting protein 1.

PAIP1 3D structure. Source: alphafold

Polyadenylate-binding protein-interacting protein 1 (PAIP1)

Acts as a coactivator in the regulation of translation initiation of poly(A)-containing mRNAs. Its stimulatory activity on translation is mediated through its action on PABPC1.

Competes with PAIP2 for binding to PABPC1. Its association with EIF4A and PABPC1 may potentiate contacts between mRNA termini.

Gene Information

Human
Gene Name:	PAIP1
Uniprot:	Q9H074
Entrez:	10605

Family

Belongs to:

No superfamily

Alternative Names

MGC12360; PABC1-interacting protein 1; PABP-interacting protein 1; PAIP-1; poly(A) binding protein interacting protein 1; Poly(A)-binding protein-interacting protein 1; polyadenylate binding protein-interacting protein 1; polyadenylate-binding protein-interacting protein 1

Molecular Weight

Mass (kDA):
53.525 kDA

Genomic Context


Human

Location:	5p12
Sequence:	5; NC_000005.10 (43526267..43557419, complement)

Subcellular Localizations

Cytoplasm.

Diseases

Hyperplasia
Cholangiocarcinoma
Rubella
Sclerosis
Muscular Dystrophy, Oculopharyngeal
Primary Lateral Sclerosis
Uterine Cervical Neoplasm
Down Syndrome
Dehydration
Amyotrophic Lateral Sclerosis
Infertility
Neoplasm Invasiveness
Malignant Tumor Of Cervix

Inflammatory Response
Malignant Neoplasms
Cervical Intraepithelial Neoplasia
Lupus Erythematosus, Systemic
Invasive Malignant Neoplasm
Precancerous Conditions
Abnormal Degeneration

Interacting Proteins

PABPC1

Pathways

Translation
Translational Initiation
Regulation Of Gene Expression
Oocyte Maturation
Mrna Processing
Regulation Of Translation
Transport
Cell Development
Dna Repair
Oxidative Phosphorylation
Nuclear Export
Spermatogenesis
Inflammatory Response

Germ Cell Development
Cell Cycle
Mrna Stabilization
Cell Growth
Pathogenesis
Pachytene
Regulation Of Mrna Processing

PTMs

Phosphorylation

Cleavage

Ubiquitination

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PAIP1

References

PMID: 9548260 by Craig A.W.B., et al. Interaction of polyadenylate-binding protein with the eIF4G homologue PAIP enhances translation.

PMID: 11051545 by Grosset C., et al. A mechanism for translationally coupled mRNA turnover: interaction between the poly(A) tail and a c-fos RNA coding determinant via a protein complex.