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Protein polybromo-1 Antibodies
AND PBRM1 ELISA kits, Protein polybromo-1 Proteins
Many biological assays use antibodies to detect Protein polybromo-1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Protein polybromo-1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Protein polybromo-1 antibodies...
Designing a Western blot for Protein polybromo-1? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the PBRM1 Western Blot GuideDesigning an IHC experiment for Protein polybromo-1? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the PBRM1 IHC GuidePBRM1 Infographic by Boster Bio
All PBRM1 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, ICC, WB
$370
Cat # A01130-1
100 μg/vial
Cat # A01130-1
100 μg/vial
Human, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M01130
100 μl
Cat # M01130
100 μl
PBRM1 Overview
Facts about Protein polybromo-1.
Protein polybromo-1 (PBRM1)
Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Required for the stability of this SWI/SNF chromatin remodeling complex SWI/SNF-B (PBAF).
Acts as a negative regulator of cell proliferation. .
Gene Information
| Human | |
|---|---|
| Gene Name: | PBRM1 |
| Uniprot: | Q86U86 |
| Entrez: | 55193 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
BAF180PB1BRG1-associated factor 180; hPB1; MGC156155; MGC156156; polybromo 1; polybromo-1D; protein polybromo-1
Molecular Weight
Mass (kDA):
192.948 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 3p21.1 |
| Sequence: | 3; NC_000003.12 (52545367..52685913, complement) |
Tissue Specificity
Widely expressed.
Subcellular Localizations
Nucleus.
Diseases
- Malignant Neoplasms
- Neoplasms
- Renal Cell Carcinoma
- Carcinoma
- Kidney Neoplasm
- Von Hippel-lindau Syndrome
- Malignant Neoplasm Of Kidney
- Conventional (clear Cell) Renal Cell Carcinoma
- Malignant Neoplasm Of Breast
- Malignant Paraganglionic Neoplasm
- Pancreatic Neoplasm
- Bipolar Disorder
- Cell Transformation, Neoplastic
Interacting Proteins
- ARID2
- CHD7
- SMARCA4
Pathways
- Chromatin Remodeling
- Methylation
- Atp-dependent Chromatin Remodeling
- Cell Proliferation
- Mitosis
- Senescence
- Cell Cycle
- Histone Acetylation
- Pathogenesis
- Osteoblast Differentiation
- Cellular Senescence
- Cell Development
- Aging
PTMs
- Acetylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PBRM1
bosterbio.com/bosterbio-gene-info-cards/PBRM1
References
PMID: 11078522 by Xue Y., et al. The human SWI/SNF-B chromatin-remodeling complex is related to yeast rsc and localizes at kinetochores of mitotic chromosomes.
PMID: 12487023 by Horikawa I., et al. cDNA cloning of the human polybromo-1 gene on chromosome 3p21.