Gastricsin Antibodies

AND PGC ELISA kits, Gastricsin Proteins

Many biological assays use antibodies to detect Gastricsin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Gastricsin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Gastricsin antibodies...

We validate the specificity of these antibodies to Gastricsin by testing them on tissues known to express PGC positively and negatively. Browse below to find the PGC antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PGC Infographic by Boster Bio

All PGC Products

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Anti-Pepsin C (F306) PGC Antibody

Western blot (WB) analysis of Pepsin C (F306) pAb at 1:500 dilution
Lane1:HepG2 whole cell lysate(40ug)
Lane2:LO2 whole cell lysate(40ug)
Lane3:SGC7901 whole cell lysate(40ug)
Lane4:PMVEC whole cell lysate(40ug)
Lane5:AML-12 whole cell lysate(40ug)

Immunohistochemistry (IHC) analyzes of Pepsin C (F306) pAb in paraffin-embedded human breast carcinoma tissue at 1:100

Human, Mouse, Rat

IHC, WB

$405
Cat # A00218
100ul

Pepsinogen II (PGC) (NM_002630) Human Recombinant Protein

Coomassie blue staining of purified PGC protein

$1249
Cat # PROTP20142
20 µg

Pepsinogen II (PGC) (NM_002630) Human Over-expression Lysate

Pepsinogen II (PGC) Human Over-expression Lysates NM_001166424

Human

$628
Cat # LS005225
20 µg, 100 µg

Anti-PGC Antibody Picoband®

Western blot analysis of PGC using anti-PGC antibody (A00218-1)

IHC analysis of PGC using anti-PGC antibody (A00218-1)

Human, Mouse, Rat

ELISA, Flow Cytometry, IF, IHC, WB

$370
Cat # A00218-1
100 µg/vial

PGC Overview

Facts about Gastricsin.

PGC 3D structure. Source: alphafold

Gastricsin (PGC)

Hydrolyzes a variety of proteins. .

Gene Information

Human
Gene Name:	PGC
Uniprot:	P20142
Entrez:	5225

Family

Belongs to:

peptidase A1 family

Alternative Names

EC 3.4.23; EC 3.4.23.3; FLJ99563; Gastricsin; PEPC; pepsin C; Pepsinogen C; pepsinogen group II; PGC; PGII; preprogastricsin; progastricsin (pepsinogen C)

Molecular Weight

Mass (kDA):
42.426 kDA

Genomic Context


Human

Location:	6p21.1
Sequence:	6; NC_000006.12 (41736711..41747401, complement)

Subcellular Localizations

Secreted.

Diseases

Malignant Neoplasms
Neoplasms
Diabetes Mellitus
Hypertensive Disease
Polyendocrinopathies, Autoimmune
Chimera Disorder
Glomerulosclerosis (disorder)
Kidney Diseases
Leukemia
Proteinuria Of Undiagnosed Cause
Gastritis
Carcinoma
Tissue Adhesions

Stomach Neoplasms
Diabetes Mellitus, Non-insulin-dependent
Pathologic Vasoconstriction
Sclerosis
Malignant Neoplasm Of Stomach
Obesity
Hypertrophy

Pathways

Glomerular Filtration
Germ Cell Development
Cell Development
Cell Migration
Germ Cell Migration
Localization
Gastrulation
Cell Proliferation
Excretion
Spermatogenesis
Cell Differentiation
Methylation
Meiosis

Pathogenesis
Oogenesis
Vasoconstriction
Tubuloglomerular Feedback
Cell Cycle
Fertilization
Transport

PTMs

Phosphorylation
Methylation
Oxidation
Cleavage
Demethylation
Glycosylation
Sulphation
Nitration
Deacetylation

Dephosphorylation
Prenylation
Acetylation
Deglycosylation
Hydroxylation
Ubiquitination
Biotinylation
Farnesylation
Amination

Geranylgeranylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PGC

References

PMID: 3335549 by Hayano T., et al. Primary structure of human pepsinogen C gene.

PMID: 2909526 by Taggart R.T., et al. Human pepsinogen C (progastricsin). Isolation of cDNA clones, localization to chromosome 6, and sequence homology with pepsinogen A.